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Details on Person GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
| Class:Id | LiteratureReference:9843922 |
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| _displayName | GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells |
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| _timestamp | 2023-09-12 15:19:59 |
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| author | [Person:9843964] Tchasovnikarova, Iva A
[Person:8943122] Timms, Richard T
[Person:9843923] Matheson, Nicholas J
[Person:9844005] Wals, Kim
[Person:5684182] Antrobus, Robin
[Person:8941808] Göttgens, Berthold
[Person:8943060] Dougan, Gordon
[Person:9844039] Dawson, Mark A
[Person:8943082] Lehner, Paul J |
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| created | [InstanceEdit:9843957] May, Bruce, 2023-09-12 |
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| journal | Science |
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| pages | 1481-1485 |
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| pubMedIdentifier | 26022416 |
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| title | GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells |
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| volume | 348 |
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| year | 2015 |
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| (literatureReference) | [Reaction:9843927] me3-K16-ATF7IP:SETDB1 and MORC2 bind MPHOSPH8 (MPP8) in HUSH complex:L1HS,L1PA2,3 heterochromatin [Homo sapiens]
[Pathway:9843970] Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex [Homo sapiens]
[Reaction:9844015] MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin [Homo sapiens]
[Reaction:9844057] SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome [Homo sapiens]
[Complex:9843933] me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] [Homo sapiens]
[Complex:9843954] HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] [Homo sapiens]
[Complex:9844009] HUSH complex [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells (9843922)
