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Details on Person Pparg:Rxra heterodimer binds target gene loci

Class:IdReaction:9843897
_displayNamePparg:Rxra heterodimer binds target gene loci
_doReleaseTRUE
_timestamp2025-11-04 01:48:57
authored[InstanceEdit:9843898] Orlic-Milacic, Marija, 2023-09-12
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9843898] Orlic-Milacic, Marija, 2023-09-12
edited[InstanceEdit:9917569] Orlic-Milacic, Marija, 2024-08-07
input[DefinedSet:9902117] Adipogenesis target genes of Pparg and Mll3/Mll4:Nucleosomes [nucleoplasm] [Mus musculus]
[Complex:9843304] Pparg2:Rxra [nucleoplasm] [Mus musculus]
internalReviewed[InstanceEdit:9907495] May, Bruce, 2024-04-10
literatureReference[LiteratureReference:381274] Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha
[LiteratureReference:9858073] H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development
[LiteratureReference:9859629] Transcriptional activation of Cidec by PPARgamma2 in adipocyte
[LiteratureReference:9842041] Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPARĪ³2
[LiteratureReference:9858985] Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
[LiteratureReference:9856190] Transcriptional coactivator PRIP, the peroxisome proliferator-activated receptor gamma (PPARgamma)-interacting protein, is required for PPARgamma-mediated adipogenesis
modified[InstanceEdit:9858316] Orlic-Milacic, Marija, 2024-01-11
[InstanceEdit:9866159] Orlic-Milacic, Marija, 2024-03-23
[InstanceEdit:9866160] Orlic-Milacic, Marija, 2024-03-23
[InstanceEdit:9902155] Orlic-Milacic, Marija, 2024-03-28
[InstanceEdit:9902209] Orlic-Milacic, Marija, 2024-03-28
[InstanceEdit:9907517] Orlic-Milacic, Marija, 2024-04-11
[InstanceEdit:9917569] Orlic-Milacic, Marija, 2024-08-07
[InstanceEdit:9917571] Orlic-Milacic, Marija, 2024-08-07
[InstanceEdit:9919218] Orlic-Milacic, Marija, 2024-08-19
[InstanceEdit:9971003] Orlic-Milacic, Marija, 2025-11-04
namePparg:Rxra heterodimer binds target gene loci
output[DefinedSet:9902159] Pparg2:Rxra:Adipogenesis genes:Nucleosomes [nucleoplasm] [Mus musculus]
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2024-09-11
reviewed[InstanceEdit:9970977] Khag, Joy, 2025-10-31
[InstanceEdit:9970978] Wang, Shu-Ping, 2025-10-31
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:9843901] R-MMU-9843897.2
structureModified[InstanceEdit:9902155] Orlic-Milacic, Marija, 2024-03-28
[InstanceEdit:9902209] Orlic-Milacic, Marija, 2024-03-28
summation[Summation:9843899] In mouse model systems of white and brown adipocyte differen...
(inferredFrom)[Reaction:9843122] PPARG:RXRA heterodimer binds target gene loci [Homo sapiens]
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No pathways have been reviewed or authored by Pparg:Rxra heterodimer binds target gene loci (9843897)
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