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Details on Person TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm]

Class:Id	Complex:9842841
_displayName	TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm]
_timestamp	2023-12-23 01:48:43
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9842827] May, Bruce, 2023-08-29
hasComponent	[EntityWithAccessionedSequence:974998] TRIM28 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:974998] TRIM28 [nucleoplasm] [Homo sapiens] [Complex:9842848] KRAB-ZFP:retroelement chromatin [nucleoplasm] [Homo sapiens] [CandidateSet:9843609] KRAB-ZFPs that bind, repress retroelements [nucleoplasm] [Homo sapiens] [Complex:9856764] Retroelement chromatin [nucleoplasm] [Homo sapiens] [Complex:427402] Nucleosome [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:181902] HIST1H4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:181902] HIST1H4 [nucleoplasm] [Homo sapiens] [CandidateSet:181899] Histone H2A [nucleoplasm] [Homo sapiens] [CandidateSet:181899] Histone H2A [nucleoplasm] [Homo sapiens] [CandidateSet:181911] Histone H2B [nucleoplasm] [Homo sapiens] [CandidateSet:181911] Histone H2B [nucleoplasm] [Homo sapiens] [DefinedSet:212293] Histone H3 [nucleoplasm] [Homo sapiens] [DefinedSet:212293] Histone H3 [nucleoplasm] [Homo sapiens] [CandidateSet:9843642] Retroelements repressed by KRAB-ZFPs [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9842831] An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons [LiteratureReference:9843604] C2H2 zinc finger proteins greatly expand the human regulatory lexicon [LiteratureReference:9842982] KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks [LiteratureReference:9843607] Multiparameter functional diversity of human C2H2 zinc finger proteins
modified	[InstanceEdit:9843688] May, Bruce, 2023-09-08 [InstanceEdit:9856776] May, Bruce, 2023-12-23
name	TRIM28:KRAB-ZFP:retroelement chromatin
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9842883] R-HSA-9842841.1
(input)	[Reaction:9842868] TRIM28 in TRIM28:KRAB-ZFP:retroelement chromatin autoSUMOylates with SUMO2 [Homo sapiens]
(output)	[Reaction:9842850] TRIM28 (KAP1) binds KRAB-ZFP in KRAB-ZFP:retroelement chromatin [Homo sapiens]
(physicalEntity)	[CatalystActivity:9856753] SUMO ligase activity of TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm]
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No pathways have been reviewed or authored by TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (9842841)