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Query author contributions in Reactome

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Details on Person Active LTK binds GRB2:TNK2

Class:IdBlackBoxEvent:9842665
_displayNameActive LTK binds GRB2:TNK2
_doReleaseTRUE
_timestamp2024-03-04 17:20:56
authored[InstanceEdit:9851215] Rothfels, Karen, 2023-10-14
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:9842653] Rothfels, Karen, 2023-08-27
edited[InstanceEdit:9851215] Rothfels, Karen, 2023-10-14
input[Complex:9842590] p-5Y LTK dimer:ALKAL1,2 [plasma membrane] [Homo sapiens]
[Complex:9842589] GRB2:TNK2 [cytosol] [Homo sapiens]
internalReviewed[InstanceEdit:9843214] Orlic-Milacic, Marija, 2023-09-06
isChimericFALSE
literatureReference[LiteratureReference:9842489] Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling
[LiteratureReference:9842507] An epidermal growth factor receptor-leukocyte tyrosine kinase chimeric receptor generates ligand-dependent growth signals through the Ras signaling pathway
[LiteratureReference:9842473] Growth and survival signals transmitted via two distinct NPXY motifs within leukocyte tyrosine kinase, an insulin receptor-related tyrosine kinase
[LiteratureReference:9842484] Crystal structures of the phosphorylated and unphosphorylated kinase domains of the Cdc42-associated tyrosine kinase ACK1
[LiteratureReference:9842435] Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas
[LiteratureReference:9842483] Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas
modified[InstanceEdit:9845039] Rothfels, Karen, 2023-09-26
[InstanceEdit:9851737] Rothfels, Karen, 2023-10-30
[InstanceEdit:9852938] Rothfels, Karen, 2023-11-08
[InstanceEdit:9852942] Rothfels, Karen, 2023-11-08
[InstanceEdit:9862075] Rothfels, Karen, 2024-02-22
[InstanceEdit:9863615] Rothfels, Karen, 2024-03-04
nameActive LTK binds GRB2:TNK2
output[Complex:9842598] Active LTK:GRB2:TNK2 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2024-03-27
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9842684] R-HSA-9842665.1
summation[Summation:9842670] Full-length LTK binds to the cytoplasmic tyrosine kinase TNK...
(hasEvent)[Pathway:9842663] Signaling by LTK [Homo sapiens]
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No pathways have been reviewed or authored by Active LTK binds GRB2:TNK2 (9842665)