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Details on Person CLIP1(1-1083)-p-6Y LTK(488-864) fusion dimer [plasma membrane]

Class:IdComplex:9842603
_displayNameCLIP1(1-1083)-p-6Y LTK(488-864) fusion dimer [plasma membrane]
_timestamp2023-08-27 21:36:52
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9842605] Rothfels, Karen, 2023-08-27
disease[Disease:1500689] cancer
[Disease:1247848] non-small cell lung carcinoma
hasComponent
literatureReference[LiteratureReference:9842438] The CLIP1-LTK fusion is an oncogenic driver in non-small-cell lung cancer
nameCLIP1(1-1083)-p-6Y LTK(488-864) fusion dimer
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9842617] R-HSA-9842603.1
(hasComponent)[Complex:9845029] CLIP1(1-1083)-p-6Y LTK(488-864) fusion dimer:PI3K [plasma membrane] [Homo sapiens]
(input)[BlackBoxEvent:9845032] CLIP1-LTK fusion binds PI3K to activate AKT [Homo sapiens]
(output)[Reaction:9842667] CLIP1-LTK fusion autophosphorylates [Homo sapiens]
(regulator)[PositiveRegulation:9845035] Positive regulation by 'CLIP1(1-1083)-p-6Y LTK(488-864) fusion dimer [plasma membrane]'
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No pathways have been reviewed or authored by CLIP1(1-1083)-p-6Y LTK(488-864) fusion dimer [plasma membrane] (9842603)
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