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Details on Person Growth and survival signals transmitted via two distinct NPXY motifs within leukocyte tyrosine kinase, an insulin receptor-related tyrosine kinase
| Class:Id | LiteratureReference:9842473 |
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| _displayName | Growth and survival signals transmitted via two distinct NPXY motifs within leukocyte tyrosine kinase, an insulin receptor-related tyrosine kinase |
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| _timestamp | 2023-08-27 21:34:57 |
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| author | [Person:5218431] Ueno, H
[Person:3857337] Sasaki, K
[Person:9842464] Kozutsumi, H
[Person:9842543] Miyagawa, K
[Person:9029063] Mitani, K
[Person:71630] Yazaki, Y
[Person:5693301] Hirai, H |
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| created | [InstanceEdit:9842478] Rothfels, Karen, 2023-08-27 |
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| journal | J Biol Chem |
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| pages | 27707-14 |
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| pubMedIdentifier | 8910363 |
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| title | Growth and survival signals transmitted via two distinct NPXY motifs within leukocyte tyrosine kinase, an insulin receptor-related tyrosine kinase |
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| volume | 271 |
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| year | 1996 |
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| (literatureReference) | [Reaction:9842641] Active LTK receptor binds SHC1 [Homo sapiens]
[Reaction:9842648] Autophosphorylation of LTK dimer:ALKAL1,2 [Homo sapiens]
[Reaction:9842651] Active LTK receptor phosphorylates SHC1 [Homo sapiens]
[Reaction:9842655] IRS1 recruits GRB2 to active LTK [Homo sapiens]
[Pathway:9842663] Signaling by LTK [Homo sapiens]
[BlackBoxEvent:9842665] Active LTK binds GRB2:TNK2 [Homo sapiens]
[Reaction:9842666] Active LTK phosphorylates IRS1 [Homo sapiens]
[Reaction:9842669] Active LTK recruits GRB2:SOS1 [Homo sapiens]
[Reaction:9842671] Active LTK binds IRS1 [Homo sapiens]
[CatalystActivityReference:9842635] protein tyrosine kinase activity of Active LTK:SHC1 [plasma membrane] Human ltk receptor tyrosine kinase binds to PLC-gamma 1, PI3-K, GAP and Raf-1 in vivo |
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