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Details on Person PSAP(195-273) dimer binds PE

Class:IdReaction:9842115
_displayNamePSAP(195-273) dimer binds PE
_doReleaseTRUE
_timestamp2025-08-13 19:23:51
authored[InstanceEdit:9842113] Stephan, Ralf, 2023-08-18
catalystActivity[CatalystActivity:9956908] phosphatidylethanolamine binding activity of PSAP(195-273) dimer [lysosomal lumen]
compartment[Compartment:161320] lysosomal lumen
[Compartment:3828048] multivesicular body, internal vesicle membrane
created[InstanceEdit:9842114] Stephan, Ralf, 2023-08-18
edited[InstanceEdit:9842112] Stephan, Ralf, 2023-08-18
input[Complex:9840482] PSAP(195-273) dimer [lysosomal lumen] [Homo sapiens]
[DefinedSet:9840942] PE 30,32,34 [multivesicular body, internal vesicle membrane]
internalReviewed[InstanceEdit:9956926] D'Eustachio, Peter, 2025-06-16
isChimericFALSE
literatureReference[LiteratureReference:9840471] Crystal structure of saposin B reveals a dimeric shell for lipid binding
modified[InstanceEdit:9937069] Stephan, Ralf, 2025-01-29
[InstanceEdit:9956913] D'Eustachio, Peter, 2025-06-16
[InstanceEdit:9956927] D'Eustachio, Peter, 2025-06-16
[InstanceEdit:9963234] D'Eustachio, Peter, 2025-08-13
namePSAP(195-273) dimer binds PE
output[Complex:9842117] PSAP(195-273):PE [lysosomal lumen] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2023-09-13
reviewed[InstanceEdit:9842118] D'Eustachio, Peter, 2023-08-18
[InstanceEdit:9963235] Hill, David P, 2025-08-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9842119] R-HSA-9842115.3
structureModified[InstanceEdit:9956913] D'Eustachio, Peter, 2025-06-16
summation[Summation:9842116] By encapsulating phosphatidylethanolamines (PE) of different...
(hasEvent)[Pathway:9840310] Glycosphingolipid catabolism [Homo sapiens]
(precedingEvent)[Reaction:9840470] PSAP(195-273) dimer:PE binds and mobilizes ligands [Homo sapiens]
(updatedInstance)[_UpdateTracker:9964619] Update Tracker - [Reaction:9842115] PSAP(195-273) dimer binds PE - v94:[removeCatalystActivity]
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No pathways have been reviewed or authored by PSAP(195-273) dimer binds PE (9842115)