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Details on Person Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPARγ2
| Class:Id | LiteratureReference:9842041 |
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| _displayName | Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPARγ2 |
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| _timestamp | 2023-08-16 20:09:46 |
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| author | [Person:9772554] Kim, Dae-Hwan
[Person:9842039] Kim, Janghyun
[Person:9842043] Kwon, Ji-Sun
[Person:9842040] Sandhu, Jaspreet
[Person:8854965] Tontonoz, Peter
[Person:5244724] Lee, Soo-Kyung
[Person:5244689] Lee, Seunghee
[Person:5244758] Lee, Jae W |
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| created | [InstanceEdit:9842042] Orlic-Milacic, Marija, 2023-08-16 |
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| journal | Cell Rep |
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| pages | 1671-1682 |
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| pubMedIdentifier | 27806304 |
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| title | Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPARγ2 |
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| volume | 17 |
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| year | 2016 |
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| (literatureReference) | [Pathway:9841922] MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis [Homo sapiens]
[Reaction:9843897] Pparg:Rxra heterodimer binds target gene loci [Mus musculus]
[Pathway:9851695] Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes [Homo sapiens]
[Pathway:9851812] MLL3 and MLL4 regulate expression of PPARG target genes in hepatic steatosis_not ready for review_merged with adipogenesis [Homo sapiens]
[BlackBoxEvent:9854142] ELOVL5 gene expression is stimulated by PPARG2:RXRA:MLL4(MLL3)-ASCOM complex [Homo sapiens]
[Reaction:9856206] Mll4-ASCOM,(Mll3-ASCOM) complex is recruited to activated Pparg:Rxra complex at target adipogenic gene loci [Mus musculus]
[BlackBoxEvent:9856352] Pparg2 transcription is stimulated by Pparg2 and Mll4 complex [Mus musculus]
[Reaction:9856368] Mll4,(Mll3)-ASCOM monomethylates nucleosomes at Pparg:Rxra-bound enhancers [Mus musculus]
[BlackBoxEvent:9906989] Acss3 gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex [Mus musculus]
[BlackBoxEvent:9906994] Agpat2 gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex [Mus musculus] |
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