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Details on Person Estrogen receptor mediates a distinct mitochondrial unfolded protein response

Class:IdLiteratureReference:9841262
_displayNameEstrogen receptor mediates a distinct mitochondrial unfolded protein response
_timestamp2023-08-11 11:31:23
author[Person:9841245] Papa, Luena
[Person:9841249] Germain, Doris
created[InstanceEdit:9841260] May, Bruce, 2023-08-11
journalJ Cell Sci
pages1396-402
pubMedIdentifier21486948
titleEstrogen receptor mediates a distinct mitochondrial unfolded protein response
volume124
year2011
(literatureReference)[RegulationReference:9856614] Positive gene expression regulation by 'p-S167-ESR1 dimer [nucleoplasm]' Estrogen receptor mediates a distinct mitochondrial unfolded protein response
[BlackBoxEvent:9841244] Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species [Homo sapiens]
[Pathway:9841251] Mitochondrial unfolded protein response (UPRmt) [Homo sapiens]
[Reaction:9841265] p-S473-AKT1 phosphorylates ESR1 on serine-167 [Homo sapiens]
[BlackBoxEvent:9841817] p-S167-ESR1 translocates from the cytosol to the nucleus [Homo sapiens]
[BlackBoxEvent:9856620] p-S167-ESR1 activates expression of HTRA2 (OMI) [Homo sapiens]
[BlackBoxEvent:9856845] p-S167-ESR1 activates expression of NRF1 [Homo sapiens]
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