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Details on Person Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2

Class:Id	Reaction:9840795
_displayName	Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2
_doRelease	TRUE
_timestamp	2025-01-29 09:11:52
authored	[InstanceEdit:9842093] Stephan, Ralf, 2023-08-17
catalystActivity	[CatalystActivity:1605789] beta-galactosidase activity of BGAL [lysosomal lumen]
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:9840794] Stephan, Ralf, 2023-07-27
edited	[InstanceEdit:9842093] Stephan, Ralf, 2023-08-17
input	[SimpleEntity:1605715] H2O [lysosomal lumen] [Complex:9840793] GM2A:GA1 [lysosomal lumen] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9842146] Role of beta-galactosidase and elastin binding protein in lysosomal and nonlysosomal complexes of patients with GM1-gangliosidosis
modified	[InstanceEdit:9842097] Stephan, Ralf, 2023-08-17 [InstanceEdit:9842148] Stephan, Ralf, 2023-08-21 [InstanceEdit:9846167] Stephan, Ralf, 2023-10-09 [InstanceEdit:9937069] Stephan, Ralf, 2025-01-29
name	Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2
output	[SimpleEntity:1605637] Gal [lysosomal lumen] [Complex:9840792] GM2A:GA2 [lysosomal lumen] [Homo sapiens]
precedingEvent	[Reaction:1605717] GM2A binds and mobilizes ligands [Homo sapiens] [BlackBoxEvent:9840579] GM1 localizes to ILV membrane [Homo sapiens] [Reaction:1605595] bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 [Homo sapiens] [Reaction:9840884] bHEXA,bHEXS hydrolyze GM2A:SM2 [Homo sapiens]
releaseDate	2023-09-13
reviewed	[InstanceEdit:9842059] D'Eustachio, Peter, 2023-08-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9840798] R-HSA-9840795.3
summation	[Summation:1605722] Ganglioside GA1 (asialo-GM1, ganglio-N-tetraosylceramide) is...
(hasEvent)	[Pathway:9840310] Glycosphingolipid catabolism [Homo sapiens]
(precedingEvent)	[Reaction:9840833] bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9853255] Update Tracker - [Reaction:9840795] Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 - v87:[modifyText]
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No pathways have been reviewed or authored by Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 (9840795)