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Details on Person Binding competition experiments indicate that TGFBR3 (uromod...
| Class:Id | Summation:9840041 |
|---|---|
| _displayName | Binding competition experiments indicate that TGFBR3 (uromod... |
| _timestamp | 2024-02-22 14:12:13 |
| created | [InstanceEdit:9840098] Tiwari, Krishna, 2023-07-13 |
| literatureReference | [LiteratureReference:9840120] Ligand binding and functional properties of betaglycan, a co-receptor of the transforming growth factor-beta superfamily. Specialized binding regions for transforming growth factor-beta and inhibin A |
| modified | [InstanceEdit:9840188] Tiwari, Krishna, 2023-07-13 [InstanceEdit:9860104] Tiwari, Krishna, 2024-01-31 [InstanceEdit:9861994] Tiwari, Krishna, 2024-02-22 |
| text | Binding competition experiments indicate that TGFBR3 (uromoduline‑related region) binds inhibin and TGF‑β with the following relative affinities: TGF‑β2 > inhibin A > TGF‑β1. The present results suggest that betaglycan ectodomain of TGFBR3 contain two independent ligand binding domains that can perform specialized functions as co‑receptors of distinct members of the TGF‑β superfamily (Espara-Lopez et al.,2001) |
| (summation) | [Reaction:9839384] Inhibin-A binding to TGFBR3 [Homo sapiens] |
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