Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person extracellular region

Class:IdCompartment:984
_displayNameextracellular region
_timestamp2018-04-19 17:11:27
accession0005576
definitionThe space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
instanceOf
modified[InstanceEdit:160533] Schmidt, EE, 2005-03-23 05:24:35
[InstanceEdit:162607] Schmidt, EE, 2005-04-01 11:06:09
[InstanceEdit:171322] Schmidt, EE, 2006-02-06 10:50:16
[InstanceEdit:258122] Kanapin, EE, 2008-03-27 12:15:20
[InstanceEdit:357819] Kanapin, EE, 2008-06-18 10:45:39
[InstanceEdit:376438] Kanapin, EE, 2008-09-08 10:23:04
[InstanceEdit:383393] Kanapin, AA, 2008-11-26 13:49:44
[InstanceEdit:386934] Mahajan, SS, 2008-11-27 13:17:17
[InstanceEdit:396309] Kanapin, EE, 2009-03-09 13:26:57
[InstanceEdit:422569] Kanapin, EE
[InstanceEdit:436347] Kanapin, EE
[InstanceEdit:447572] Kanapin, EE
[InstanceEdit:526073] Kanapin, AA
[InstanceEdit:528085] Kanapin, AA
[InstanceEdit:615500] Kanapin, AA
[InstanceEdit:797782] Kanapin, AA
[InstanceEdit:937668] Yung, CK
[InstanceEdit:1042299] Yung, CK
[InstanceEdit:1220942] Yung, CK
[InstanceEdit:1301009] Yung, CK
[InstanceEdit:1301023] Yung, CK
[InstanceEdit:1552540] Yung, CK
[InstanceEdit:1996004] Yung, CK
[InstanceEdit:2132408] Weiser, JD
[InstanceEdit:2133145] Weiser, JD
[InstanceEdit:2266118] Weiser, JD
[InstanceEdit:2266147] Weiser, JD
[InstanceEdit:2454362] Weiser, JD
[InstanceEdit:2455542] Weiser, JD
[InstanceEdit:2587907] Weiser, JD
[InstanceEdit:3132285] Weiser, JD
[InstanceEdit:3445953] Weiser, JD
[InstanceEdit:4341211] Weiser, JD
[InstanceEdit:5083267] Weiser, JD
[InstanceEdit:5263134] Weiser, JD
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9689214] Cook, Justin, 2020-05-15
[InstanceEdit:9715950] Shorser, Solomon, 2021-02-17
[InstanceEdit:9730069] Shorser, Solomon, 2021-05-05
[InstanceEdit:9750511] Weiser, JD, 2021-08-11
[InstanceEdit:9758049] Weiser, JD, 2021-11-08
[InstanceEdit:9767446] Wright, Adam, 2022-02-25
[InstanceEdit:9773560] Weiser, Joel, 2022-05-04
[InstanceEdit:9910546] Weiser, Joel, 2024-05-14
[InstanceEdit:9917761] Weiser, Joel, 2024-08-09
[InstanceEdit:9926777] Weiser, Joel, 2024-11-03
[InstanceEdit:9939260] Weiser, Joel, 2025-02-21
[InstanceEdit:9948590] Weiser, Joel, 2025-05-21
[InstanceEdit:9963890] Weiser, Joel, 2025-08-15
[InstanceEdit:9970828] Weiser, Joel, 2025-10-31
[InstanceEdit:9983368] Weiser, Joel, 2026-02-22
[InstanceEdit:9989188] Weiser, Joel, 2026-05-15
nameextracellular region
referenceDatabase[ReferenceDatabase:1] GO
(compartment)[Reaction:74101] Photons induce isomerization of 11c-retinyl to at-retinyl [Homo sapiens]
[Reaction:75238] TRAIL binds TRAIL receptors [Homo sapiens]
[Reaction:75244] FASL binds FAS Receptor [Homo sapiens]
[Reaction:109278] NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP [Homo sapiens]
[Reaction:109281] uridine 5'-monophosphate (UMP) + H2O => uridine + orthophosphate [Rattus norvegicus]
[Reaction:109284] guanosine 5'-monophosphate (GMP) + H2O => guanosine + orthophosphate [Rattus norvegicus]
[Reaction:109287] inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate [Rattus norvegicus]
[Reaction:109290] cytidine 5'-monophosphate (CMP) + H2O => cytidine + orthophosphate [Rattus norvegicus]
[Reaction:109291] CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] [Homo sapiens]
[Reaction:109293] thymidine 5'-monophosphate (TMP) + H2O => thymidine + orthophosphate [Rattus norvegicus]
List all 13211 refering instances
(componentOf)[GO_CellularComponent:4318] insulin-like growth factor binding protein complex
[GO_CellularComponent:13255] immunoglobulin complex, circulating
[GO_CellularComponent:16262] fibrinogen complex
[GO_CellularComponent:17093] classical-complement-pathway C3/C5 convertase complex
[GO_CellularComponent:17094] complement component C1 complex
[GO_CellularComponent:17114] larval serum protein complex
[GO_CellularComponent:17120] external encapsulating structure
[GO_CellularComponent:20037] intercellular bridge
[GO_CellularComponent:77684] apoplast
[GO_CellularComponent:78529] activin complex
List all 40 refering instances
(goCellularComponent)[CandidateSet:9916250] Expansins [extracellular region] [Oryza sativa]
[EntityWithAccessionedSequence:9924534] EXPA33 [extracellular region] [Oryza sativa subsp. japonica]
(includedLocation)[Complex:354079] Focal Adhesion/Focal contacts [plasma membrane] [Homo sapiens]
[Complex:354157] Vinculin bound to alphaIIbbeta3 [plasma membrane] [Homo sapiens]
[Complex:447186] IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 [plasma membrane] [Homo sapiens]
[Complex:448378] IL25 dimer:IL17RA:IL17RB [plasma membrane] [Homo sapiens]
[Complex:448403] IL17RA:IL17RC:IL17A dimer,L17F dimer,IL17A:IL17F [plasma membrane] [Homo sapiens]
[Complex:448411] IL22:IL22RA1:JAK1 [plasma membrane] [Homo sapiens]
[Complex:448431] IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] [Homo sapiens]
[Complex:448565] IL31:IL31RA:JAK1:OSMR:JAK1 [plasma membrane] [Homo sapiens]
[Complex:448571] IL33:IL1RL1:IL1RAP-1 [plasma membrane] [Homo sapiens]
[Complex:448601] IL1RL1:IL33 [plasma membrane] [Homo sapiens]
List all 153 refering instances
(surroundedBy)[Compartment:876] plasma membrane
[Compartment:20798] cell outer membrane
[Compartment:24778] basolateral plasma membrane
[Compartment:24781] apical plasma membrane
[Compartment:25409] peptidoglycan-based cell wall
[Compartment:25413] Gram-positive-bacterium-type cell wall
[Compartment:74000] photoreceptor outer segment membrane
[Compartment:159997] extracellular matrix
[Compartment:161429] phagocytic cup
[Compartment:171242] viral envelope
List all 23 refering instances
[Change default viewing format]
No pathways have been reviewed or authored by extracellular region (984)