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Details on Person APP [mitochondrial inner membrane]

Class:Id	EntityWithAccessionedSequence:9839060
_displayName	APP [mitochondrial inner membrane]
_timestamp	2023-06-30 18:25:40
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:9839143] May, Bruce, 2023-06-30
endCoordinate	695
literatureReference	[LiteratureReference:9839085] Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells [LiteratureReference:9839123] Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
name	APP fullName evidence="150"Amyloid-beta precursor protein A4_HUMAN APP695
referenceEntity	[ReferenceIsoform:143653] UniProt:P05067-4 APP [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9839152] R-HSA-9839060.1
startCoordinate	18
(hasComponent)	[Complex:9839100] HTRA2:APP [mitochondrial inner membrane] [Homo sapiens]
(input)	[BlackBoxEvent:9839072] HTRA2 degrades APP (Amyloid-beta precursor protein) [Homo sapiens] [Reaction:9839092] HTRA2 binds APP (Amyloid-beta precursor protein) [Homo sapiens]
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No pathways have been reviewed or authored by APP [mitochondrial inner membrane] (9839060)