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Details on Person Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy
| Class:Id | LiteratureReference:9838797 |
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| _displayName | Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy |
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| _timestamp | 2023-06-26 17:11:34 |
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| author | [Person:9687077] Ordureau, Alban
[Person:9838799] Heo, Jin-Mi
[Person:5634955] Duda, David M
[Person:8953635] Paulo, Joao A
[Person:5682900] Olszewski, Jennifer L
[Person:9687076] Yanishevski, David
[Person:9677777] Rinehart, Jesse
[Person:5634959] Schulman, Brenda A
[Person:2859007] Harper, J Wade |
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| created | [InstanceEdit:9838783] Shamovsky, Veronica, 2023-06-26 |
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| journal | Proc Natl Acad Sci U S A |
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| pages | 6637-42 |
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| pubMedIdentifier | 25969509 |
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| title | Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy |
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| volume | 112 |
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| year | 2015 |
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| (literatureReference) | [Reaction:9834945] PINK1 phosphorylates Ub on MOM proteins [Homo sapiens]
[BlackBoxEvent:9835009] PRKN binds p-S-Ub:MOM proteins [Homo sapiens]
[Reaction:9835011] PINK1 phosphorylates PRKN at S65 [Homo sapiens]
[Summation:5205639] This is the process of selective removal of damaged mitochon...
[Summation:9838794] Upon mitochondrial damage, activated PINK1 accumulates at th...
[Summation:9839455] A loss in mitochondrial membrane potential leads to the PINK...
[Summation:9839893] The E3 ubiquitin protein ligase parkin (PRKN) translocates t... |
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