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Details on Person Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering

Class:IdLiteratureReference:9838789
_displayNamePhosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering
_timestamp2023-06-26 17:11:30
author[Person:9834929] Shiba-Fukushima, Kahori
[Person:9838803] Arano, Taku
[Person:9838777] Matsumoto, Gen
[Person:9838778] Inoshita, Tsuyoshi
[Person:9838804] Yoshida, Shigeharu
[Person:3004731] Ishihama, Yasushi
[Person:9838802] Ryu, Kwon-Yul
[Person:9838779] Nukina, Nobuyuki
[Person:5658564] Hattori, Nobutaka
[Person:9838798] Imai, Yuzuru
created[InstanceEdit:9838783] Shamovsky, Veronica, 2023-06-26
journalPLoS Genet
pagese1004861
pubMedIdentifier25474007
titlePhosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering
volume10
year2014
(literatureReference)[CatalystActivityReference:9839813] protein serine/threonine kinase activity of p-S228,S402-PINK1:p-S228,S402-PINK1 [mitochondrial outer membrane] Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering
[Summation:5205639] This is the process of selective removal of damaged mitochon...
[Summation:9838794] Upon mitochondrial damage, activated PINK1 accumulates at th...
[Summation:9839455] A loss in mitochondrial membrane potential leads to the PINK...
[Summation:9839893] The E3 ubiquitin protein ligase parkin (PRKN) translocates t...
[Reaction:9834945] PINK1 phosphorylates Ub on MOM proteins [Homo sapiens]
[BlackBoxEvent:9835009] PRKN binds p-S-Ub:MOM proteins [Homo sapiens]
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