Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person SYK binds the activated BCR

Class:Id	Reaction:983700
_displayName	SYK binds the activated BCR
_doRelease	TRUE
_timestamp	2018-08-09 15:36:01
authored	[InstanceEdit:983688] May, B, 2010-10-31
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:983694] May, B, 2010-11-02
edited	[InstanceEdit:983688] May, B, 2010-10-31
input	[Complex:983691] Antigen:p-BCR [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:58268] SYK [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:453188] Molecular mechanism of the Syk activation switch [LiteratureReference:983521] Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation [LiteratureReference:983486] Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex [LiteratureReference:983507] Reconstitution of the B cell antigen receptor signaling components in COS cells
modified	[InstanceEdit:1112667] May, B, 2010-12-07 [InstanceEdit:1169093] May, B, 2011-01-11 [InstanceEdit:1169616] May, B, 2011-01-19 [InstanceEdit:1977928] May, B, 2011-11-08 [InstanceEdit:2010554] May, B, 2011-11-22 [InstanceEdit:2038845] May, B, 2012-01-10 [InstanceEdit:2108989] May, B, 2012-02-11 [InstanceEdit:5251728] May, B, 2014-02-05 [InstanceEdit:9616036] May, Bruce, 2018-08-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SYK binds the activated BCR Recruitment of SYK to the Activated B Cell Receptor
output	[Complex:983693] Antigen:p-BCR:SYK [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:983709] LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) [Homo sapiens] [Reaction:983696] The Immunoglobulin of the BCR binds antigen [Homo sapiens]
releaseDate	2012-03-13
reviewed	[InstanceEdit:2108988] Wienands, J, 2012-02-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2158179] R-HSA-983700.3
summation	[Summation:1168929] The SYK protein tyrosine kinase binds specifically to phosph...
(hasEvent)	[Pathway:983695] Antigen activates B Cell Receptor (BCR) leading to generation of second messengers [Homo sapiens]
(precedingEvent)	[Reaction:983707] SYK autophosphorylates at the activated BCR [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by SYK binds the activated BCR (983700)