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Details on Person Activated protein kinase R (PKR, EIF2AK2) phosphorylates tum...
| Class:Id | Summation:9836342 |
|---|---|
| _displayName | Activated protein kinase R (PKR, EIF2AK2) phosphorylates tum... |
| _timestamp | 2023-07-06 09:15:20 |
| created | [InstanceEdit:9836352] Stephan, Ralf, 2023-05-26 |
| modified | [InstanceEdit:9839458] Stephan, Ralf, 2023-07-06 |
| text | Activated protein kinase R (PKR, EIF2AK2) phosphorylates tumor antigen p53 (TP53) at S392, but it is unclear if subsequent p53 activation is due to this modification or to the SUMOylation of p53 by a PRKRA/PKR/UBE2I complex (Yeung et al, 1998; Cuddihy et al, 1999a; Cuddihy et al, 1999b; Rahman et al, 2009; Yoon et al, 2009; Bennett et al, 2012; Song et al, 2015). |
| (summation) | [Reaction:9836362] p-PKR dimer phosphorylates TP53 tetramer [Homo sapiens] |
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No pathways have been reviewed or authored by Activated protein kinase R (PKR, EIF2AK2) phosphorylates tum... (9836342)
