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Details on Person Expression of TFAP2A in the neural plate border

Class:IdBlackBoxEvent:9835255
_displayNameExpression of TFAP2A in the neural plate border
_doReleaseTRUE
_timestamp2023-10-28 06:33:44
authored[InstanceEdit:9834901] May, Bruce, 2023-05-10
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9835232] May, Bruce, 2023-05-12
edited[InstanceEdit:9834901] May, Bruce, 2023-05-10
inferredFrom
input[EntityWithAccessionedSequence:9835219] TFAP2A gene [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9837443] Matthews, Lisa, 2023-06-14
isChimericFALSE
literatureReference[LiteratureReference:9835254] WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate
[LiteratureReference:9835241] Bone morphogenetic protein 4 promotes craniofacial neural crest induction from human pluripotent stem cells
[LiteratureReference:9835495] A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages
modified[InstanceEdit:9835307] May, Bruce, 2023-05-12
[InstanceEdit:9835512] May, Bruce, 2023-05-15
[InstanceEdit:9835563] May, Bruce, 2023-05-15
[InstanceEdit:9836088] May, Bruce, 2023-05-22
[InstanceEdit:9836279] May, Bruce, 2023-05-24
[InstanceEdit:9837445] May, Bruce, 2023-06-14
[InstanceEdit:9851582] May, Bruce, 2023-10-28
nameExpression of TFAP2A in the neural plate border
output[EntityWithAccessionedSequence:8864280] TFAP2A [nucleoplasm] [Homo sapiens]
regulatedBy[PositiveGeneExpressionRegulation:9754242] Positive gene expression regulation by 'BMP4 dimer [extracellular region]'
[PositiveGeneExpressionRegulation:9793404] Positive gene expression regulation by 'WNT3A [extracellular region]'
regulationReference[RegulationReference:9836024] Positive gene expression regulation by 'BMP4 dimer [extracellular region]' Bone morphogenetic protein 4 promotes craniofacial neural crest induction from human pluripotent stem cells
[RegulationReference:9836019] Positive gene expression regulation by 'WNT3A [extracellular region]' WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate
releaseDate2023-12-06
reviewed[InstanceEdit:9851580] Gunhaga, Lena, 2023-10-28
[InstanceEdit:9851576] Patthey, Cédric, 2023-10-28
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9835269] R-HSA-9835255.1
structureModified[InstanceEdit:9836088] May, Bruce, 2023-05-22
summation[Summation:9836001] Activation of canonical WNT signaling by inhibition of GSK3 ...
(hasEvent)[Pathway:9834899] Specification of the neural plate border [Homo sapiens]
(precedingEvent)[Reaction:9835795] TFAP2A binds the PAX3 gene [Homo sapiens]
[Reaction:9836270] TFAP2A binds TFAP2C [Homo sapiens]
[Reaction:9836275] TFAP2A binds TFAP2B [Homo sapiens]
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No pathways have been reviewed or authored by Expression of TFAP2A in the neural plate border (9835255)
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