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Details on Person protein serine/threonine kinase activity of p-S228,S402-PINK1:p-S228,S402-PINK1 [mitochondrial outer membrane]

Class:Id	CatalystActivity:9834937
_displayName	protein serine/threonine kinase activity of p-S228,S402-PINK1:p-S228,S402-PINK1 [mitochondrial outer membrane]
_timestamp	2023-05-11 08:11:42
activeUnit	[EntityWithAccessionedSequence:9834051] p-S228,S402-PINK1 [mitochondrial outer membrane] [Homo sapiens]
activity	[GO_MolecularFunction:4028] protein serine/threonine kinase activity
created	[InstanceEdit:9834926] Shamovsky, Veronica, 2023-05-11
modified	[InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15
physicalEntity	[Complex:9834066] p-S228,S402-PINK1:p-S228,S402-PINK1 [mitochondrial outer membrane] [Homo sapiens]
(catalystActivity)	[Reaction:9834945] PINK1 phosphorylates Ub on MOM proteins [Homo sapiens] [Reaction:9835011] PINK1 phosphorylates PRKN at S65 [Homo sapiens] [CatalystActivityReference:9834931] protein serine/threonine kinase activity of p-S228,S402-PINK1:p-S228,S402-PINK1 [mitochondrial outer membrane] PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria [CatalystActivityReference:9839813] protein serine/threonine kinase activity of p-S228,S402-PINK1:p-S228,S402-PINK1 [mitochondrial outer membrane] Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering
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No pathways have been reviewed or authored by protein serine/threonine kinase activity of p-S228,S402-PINK1:p-S228,S402-PINK1 [mitochondrial outer membrane] (9834937)