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Details on Person Binding of interferon-inducible double-stranded RNA-dependen...
| Class:Id | Summation:9834785 |
|---|---|
| _displayName | Binding of interferon-inducible double-stranded RNA-dependen... |
| _timestamp | 2023-08-16 09:44:33 |
| created | [InstanceEdit:9834828] Stephan, Ralf, 2023-05-10 |
| modified | [InstanceEdit:9834874] Stephan, Ralf, 2023-05-10 [InstanceEdit:9839457] Stephan, Ralf, 2023-07-06 [InstanceEdit:9841967] Stephan, Ralf, 2023-08-16 |
| text | Binding of interferon-inducible double-stranded RNA-dependent protein kinase activator A (PRKRA, PACT) to PKR leads to activation of PKR by dimerization and autophosphorylation. The strength of the PRKRA-PKR interaction depends on PRKRA dimerization and its stress-induced phosphorylation on serine residues 246 and 287 (Patel & Sen, 1998; Peters et al, 2001; Huang et al, 2002; Peters et al, 2006; Chukwurah et al, 2018). |
| (summation) | [Reaction:9834821] p-PRKRA dimer binds PKR [Homo sapiens] |
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No pathways have been reviewed or authored by Binding of interferon-inducible double-stranded RNA-dependen... (9834785)
