Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person Poly(rC) binding protein 2 (PCB2), is one of the negative re...
| Class:Id | Summation:983443 |
|---|---|
| _displayName | Poly(rC) binding protein 2 (PCB2), is one of the negative re... |
| _timestamp | 2024-11-05 11:22:06 |
| created | [InstanceEdit:983447] Garapati, P V, 2010-11-01 |
| literatureReference | [LiteratureReference:983448] PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4 |
| modified | [InstanceEdit:9927237] Shamovsky, Veronica, 2024-11-05 |
| text | Poly(rC) binding protein 2 (PCB2), is one of the negative regulators of RIG-I (DDX58) and IFIH1 (MDA5) signaling pathways. It interacts with MAVS (IPS-1) and mediates its ubiquitin/proteasomal degradation by recruiting E3 ligase AIP4 (ITCH). |
| (summation) | [Reaction:990528] Interaction of PCBP2 with MAVS [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Poly(rC) binding protein 2 (PCB2), is one of the negative re... (983443)
