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Details on Person Human respiratory syncytial virus contains 10 genes which ar...
| Class:Id | Summation:9832250 |
|---|---|
| _displayName | Human respiratory syncytial virus contains 10 genes which ar... |
| _timestamp | 2023-11-07 15:05:42 |
| created | [InstanceEdit:9832252] Stephan, Ralf, 2023-03-30 |
| modified | [InstanceEdit:9832605] Stephan, Ralf, 2023-04-04 [InstanceEdit:9838773] Orlic-Milacic, Marija, 2023-06-26 [InstanceEdit:9839741] Stephan, Ralf, 2023-07-10 [InstanceEdit:9852831] Orlic-Milacic, Marija, 2023-11-07 |
| text | Human respiratory syncytial virus contains 10 genes which are translated into 11 proteins, of which 2 have translation isoforms due to use of alternative translation initiation codons. These proteins function in viral replication and host interaction. Fusion protein F, glycoprotein G, and both variants of small hydrophobic protein, SH and SHt, get glycosylated and F, G, and SH later migrate to the plasma membrane where virion assembly takes place. Matrix protein M first translocates to the nucleus and back to cytosol before serving as a scaffold at the assembly site. M2-1 is also found in the nucleus. Phosphorylations, partially transient, appear to be necessary for oligomerization and function of the SH, N, P, M, and M2-1 proteins (Gan & Torres, 2011; McLellan et al, 2013; Muniyandi et al, 2018; Anderson et al, 2021). |
| (summation) | [Pathway:9828806] Maturation of hRSV A proteins [Homo sapiens] |
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No pathways have been reviewed or authored by Human respiratory syncytial virus contains 10 genes which ar... (9832250)
