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Details on Person Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex
Class:Id Reaction:983161
_displayName Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex
_doRelease TRUE
_timestamp 2024-05-16 16:47:50
authored [InstanceEdit:983164] Garapati, P V, 2010-10-29
compartment [Compartment:5263265] lumenal side of endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created [InstanceEdit:983151] Garapati, P V, 2010-10-29
edited [InstanceEdit:983164] Garapati, P V, 2010-10-29
input [Complex:8951496] Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] [Homo sapiens]
isChimeric FALSE
literatureReference [LiteratureReference:1262963] The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding [LiteratureReference:982932] Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution [LiteratureReference:982974] Structural definition of the H-2Kd peptide-binding motif [LiteratureReference:1262946] Peptide-receptive major histocompatibility complex class I molecules cycle between endoplasmic reticulum and cis-Golgi in wild-type lymphocytes [LiteratureReference:1262961] Calreticulin-dependent recycling in the early secretory pathway mediates optimal peptide loading of MHC class I molecules
modified [InstanceEdit:985506] Garapati, P V, 2010-11-03 [InstanceEdit:1004532] Garapati, P V, 2010-11-09 [InstanceEdit:1027408] Garapati, P V, 2010-11-18 [InstanceEdit:1093901] Matthews, L, 2010-11-29 [InstanceEdit:1213481] Garapati, P V, 2011-02-11 [InstanceEdit:1222763] Garapati, P V, 2011-02-28 [InstanceEdit:1262955] Garapati, P V, 2011-05-05 [InstanceEdit:1295503] Garapati, P V, 2011-05-16 [InstanceEdit:8951501] Jupe, Steve, 2016-12-07 [InstanceEdit:8951708] Jupe, Steve, 2016-12-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9910706] D'Eustachio, Peter, 2024-05-16
name Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex
output [Complex:983132] Antigen peptide bound class I MHC:BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:901028] PDIA3 [endoplasmic reticulum lumen] [Homo sapiens] [Complex:983113] TAP [endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:983083] TAPBP [lumenal side of endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:985502] CALR [lumenal side of endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent
releaseDate 2011-06-14
reviewed [InstanceEdit:1213482] Elliott, T, 2011-02-10
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1357648] R-HSA-983161.4
summation [Summation:8951707] Upon peptide binding the class I MHC molecule releases from ...
(hasEvent) [Pathway:983170] Antigen Presentation: Folding, assembly and peptide loading of class I MHC [Homo sapiens]
(precedingEvent) [Reaction:983138] Transport of MHC heterotrimer to ER exit site [Homo sapiens]
(updatedInstance) [_UpdateTracker:9781792] Update Tracker - [Reaction:983161] Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex - v60:[add_removeInput, add_removeSummation]
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