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Details on Person Interaction of E3 with substrate and E2-Ub complex

Class:Id	Reaction:983157
_displayName	Interaction of E3 with substrate and E2-Ub complex
_doRelease	TRUE
_timestamp	2016-01-08 12:17:18
authored	[InstanceEdit:983164] Garapati, P V, 2010-10-29
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:983151] Garapati, P V, 2010-10-29
edited	[InstanceEdit:983164] Garapati, P V, 2010-10-29
input	[CandidateSet:976075] E3 ligases in proteasomal degradation [cytosol] [Homo sapiens] [Complex:976165] Ubiquitin:E2 conjugating enzymes [cytosol] [Homo sapiens] [OtherEntity:983035] antigenic substrate [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:982870] RING domain E3 ubiquitin ligases [LiteratureReference:982903] U-box proteins as a new family of ubiquitin ligases [LiteratureReference:982919] A novel family of membrane-bound E3 ubiquitin ligases [LiteratureReference:8850915] Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system
modified	[InstanceEdit:1004532] Garapati, P V, 2010-11-09 [InstanceEdit:1027408] Garapati, P V, 2010-11-18 [InstanceEdit:1093901] Matthews, L, 2010-11-29 [InstanceEdit:1213481] Garapati, P V, 2011-02-11 [InstanceEdit:1222763] Garapati, P V, 2011-02-28 [InstanceEdit:1295503] Garapati, P V, 2011-05-16 [InstanceEdit:8851658] Garapati, Phani Vijay, 2016-01-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Interaction of E3 with substrate and E2-Ub complex
output	[Complex:983126] Ag-substrate:E3:E2:Ub [cytosol] [Homo sapiens]
precedingEvent	[Reaction:983152] Transfer of ubiquitin from E1 to E2 [Homo sapiens] [Reaction:983153] E1 mediated ubiquitin activation [Homo sapiens]
releaseDate	2011-06-14
reviewed	[InstanceEdit:1213482] Elliott, T, 2011-02-10
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1357588] R-HSA-983157.3
summation	[Summation:982860] Ubiquitin E3 ligases confer specificity to ubiquitination by...
(hasEvent)	[Pathway:983168] Antigen processing: Ubiquitination & Proteasome degradation [Homo sapiens]
(precedingEvent)	[Reaction:983140] Transfer of Ub from E2 to substrate and release of E2 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783375] Update Tracker - [Reaction:983157] Interaction of E3 with substrate and E2-Ub complex - v56:[addLiteratureReference]
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No pathways have been reviewed or authored by Interaction of E3 with substrate and E2-Ub complex (983157)