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Details on Person Proteasomal cleavage of substrate
Class:Id BlackBoxEvent:983150 _displayName Proteasomal cleavage of substrate _doRelease TRUE _timestamp 2016-10-21 22:04:28 authored [InstanceEdit:983164] Garapati, P V, 2010-10-29 catalystActivity [CatalystActivity:68824] endopeptidase activity of 26S proteasome [cytosol] compartment [Compartment:70101] cytosol created [InstanceEdit:983151] Garapati, P V, 2010-10-29 edited [InstanceEdit:983164] Garapati, P V, 2010-10-29 input [OtherEntity:983123] K48polyUb-antigenic substrate [cytosol] isChimeric FALSE literatureReference [LiteratureReference:982846] Proteasome and peptidase function in MHC-class-I-mediated antigen presentation [LiteratureReference:982892] The proteasome and MHC class I antigen processing [LiteratureReference:982999] 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide [LiteratureReference:982907] Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide [LiteratureReference:982859] Post-proteasomal antigen processing for major histocompatibility complex class I presentation [LiteratureReference:983431] Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII modified [InstanceEdit:983177] Jupe, S, 2010-10-29 [InstanceEdit:983423] Garapati, P V, 2010-11-01 [InstanceEdit:983434] Garapati, P V, 2010-11-01 [InstanceEdit:1004533] Garapati, P V, 2010-11-09 [InstanceEdit:1027409] Garapati, P V, 2010-11-18 [InstanceEdit:1093901] Matthews, L, 2010-11-29 [InstanceEdit:1213483] Garapati, P V, 2011-02-11 [InstanceEdit:1222763] Garapati, P V, 2011-02-28 [InstanceEdit:1234156] May, B, 2011-03-18 [InstanceEdit:1295503] Garapati, P V, 2011-05-16 [InstanceEdit:8942991] D'Eustachio, Peter, 2016-10-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name Proteasomal cleavage of substrate output [DefinedSet:113595] Ub [cytosol] [Homo sapiens] [SimpleEntity:983036] precursor peptide fragment (>16 aa) [cytosol] [SimpleEntity:8942986] L-amino acid [cytosol] [SimpleEntity:983032] oligopeptide fragment (8-16aa) [cytosol] precedingEvent
releaseDate 2011-06-14 reviewed [InstanceEdit:1213482] Elliott, T, 2011-02-10 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:1357603] R-HSA-983150.3 summation [Summation:982876] The 26S proteasome complex consists of the 20S catalytic cor... (hasEvent) [Pathway:983168] Antigen processing: Ubiquitination & Proteasome degradation [Homo sapiens] (precedingEvent) [Reaction:983144] Transport of Antigen peptide in to ER [Homo sapiens] [BlackBoxEvent:983162] Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases [Homo sapiens] [BlackBoxEvent:8940641] THOP1 cleaves oligopeptide fragment (8-16aa) [Homo sapiens] (updatedInstance) [_UpdateTracker:9782621] Update Tracker - [BlackBoxEvent:983150] Proteasomal cleavage of substrate - v59:[add_removeOutput] [_UpdateTracker:9919520] Update Tracker - [BlackBoxEvent:983150] Proteasomal cleavage of substrate - v90:[modifyText]
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