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Details on Person Release of E3 from polyubiquitinated substrate

Class:Id	Reaction:983147
_displayName	Release of E3 from polyubiquitinated substrate
_doRelease	TRUE
_timestamp	2011-06-10 08:48:33
authored	[InstanceEdit:983164] Garapati, P V, 2010-10-29
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:983151] Garapati, P V, 2010-10-29
edited	[InstanceEdit:983164] Garapati, P V, 2010-10-29
input	[Complex:983134] E3:K48-polyubiquitinated substrate [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:982919] A novel family of membrane-bound E3 ubiquitin ligases [LiteratureReference:982903] U-box proteins as a new family of ubiquitin ligases [LiteratureReference:982870] RING domain E3 ubiquitin ligases
modified	[InstanceEdit:1004532] Garapati, P V, 2010-11-09 [InstanceEdit:1027408] Garapati, P V, 2010-11-18 [InstanceEdit:1093901] Matthews, L, 2010-11-29 [InstanceEdit:1213481] Garapati, P V, 2011-02-11 [InstanceEdit:1222763] Garapati, P V, 2011-02-28 [InstanceEdit:1295503] Garapati, P V, 2011-05-16 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Release of E3 from polyubiquitinated substrate
output	[OtherEntity:983123] K48polyUb-antigenic substrate [cytosol] [CandidateSet:976075] E3 ligases in proteasomal degradation [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:983156] Polyubiquitination of substrate [Homo sapiens] [Reaction:983140] Transfer of Ub from E2 to substrate and release of E2 [Homo sapiens]
releaseDate	2011-06-14
reviewed	[InstanceEdit:1213482] Elliott, T, 2011-02-10
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1357660] R-HSA-983147.2
summation	[Summation:982884] K48 polyubiquitinated substrate dissociates from E3 to becom...
(hasEvent)	[Pathway:983168] Antigen processing: Ubiquitination & Proteasome degradation [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:983150] Proteasomal cleavage of substrate [Homo sapiens]
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No pathways have been reviewed or authored by Release of E3 from polyubiquitinated substrate (983147)