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Details on Person Transport of Antigen peptide in to ER
Class:Id Reaction:983144 _displayName Transport of Antigen peptide in to ER _doRelease TRUE _timestamp 2024-06-13 02:19:10 authored [InstanceEdit:983164] Garapati, P V, 2010-10-29 catalystActivity [CatalystActivity:983154] ABC-type peptide antigen transporter activity of TAP [endoplasmic reticulum membrane] catalystActivityReference [CatalystActivityReference:9643445] peptide antigen-transporting ATPase activity of TAP [endoplasmic reticulum membrane] The ABC-transporter signature motif is required for peptide translocation but not peptide binding by TAP compartment [Compartment:17957] endoplasmic reticulum lumen [Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane created [InstanceEdit:983151] Garapati, P V, 2010-10-29 edited [InstanceEdit:983164] Garapati, P V, 2010-10-29 input [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:29356] H2O [cytosol] [SimpleEntity:983032] oligopeptide fragment (8-16aa) [cytosol] isChimeric FALSE literatureReference [LiteratureReference:982910] The ABC-transporter signature motif is required for peptide translocation but not peptide binding by TAP [LiteratureReference:982934] Kinetic analysis of peptide binding to the TAP transport complex: evidence for structural rearrangements induced by substrate binding [LiteratureReference:982968] Antigen processing and presentation: TAPping into ABC transporters [LiteratureReference:982993] Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter modified [InstanceEdit:983175] Garapati, P V, 2010-10-29 [InstanceEdit:983423] Garapati, P V, 2010-11-01 [InstanceEdit:1004532] Garapati, P V, 2010-11-09 [InstanceEdit:1027408] Garapati, P V, 2010-11-18 [InstanceEdit:1093901] Matthews, L, 2010-11-29 [InstanceEdit:1213481] Garapati, P V, 2011-02-11 [InstanceEdit:1222763] Garapati, P V, 2011-02-28 [InstanceEdit:1295503] Garapati, P V, 2011-05-16 [InstanceEdit:9034317] Orlic-Milacic, Marija, 2018-01-03 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9913251] Shamovsky, Veronica, 2024-06-13 name Transport of Antigen peptide in to ER output [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29372] Pi [cytosol] [SimpleEntity:29372] Pi [cytosol] [SimpleEntity:983034] oligopeptide fragment [endoplasmic reticulum lumen] precedingEvent
releaseDate 2011-06-14 reviewed [InstanceEdit:1213482] Elliott, T, 2011-02-10 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:1357544] R-HSA-983144.5 summation [Summation:982881] Transporter associated with antigen processing (TAP) is a he... (hasEvent) [Pathway:983170] Antigen Presentation: Folding, assembly and peptide loading of class I MHC [Homo sapiens] (precedingEvent) [BlackBoxEvent:983158] Trimming of peptides in ER [Homo sapiens] (updatedInstance) [_UpdateTracker:9919356] Update Tracker - [Reaction:983144] Transport of Antigen peptide in to ER - v90:[modifyText]
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