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Details on Person Formation of peptide loading complex (PLC)
Class:Id Reaction:983142
_displayName Formation of peptide loading complex (PLC)
_doRelease TRUE
_timestamp 2024-05-16 16:47:52
authored [InstanceEdit:983164] Garapati, P V, 2010-10-29
compartment [Compartment:5263265] lumenal side of endoplasmic reticulum membrane [Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created [InstanceEdit:983151] Garapati, P V, 2010-10-29
edited [InstanceEdit:983164] Garapati, P V, 2010-10-29
input [Polymer:983323] BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] [Homo sapiens] [Complex:983136] MHC HC:B2M:Erp57 [lumenal side of endoplasmic reticulum membrane] [Homo sapiens] [Complex:983113] TAP [endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:983083] TAPBP [lumenal side of endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:985502] CALR [lumenal side of endoplasmic reticulum membrane] [Homo sapiens]
isChimeric FALSE
literatureReference [LiteratureReference:982979] Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer [LiteratureReference:983316] The peptide-loading complex--antigen translocation and MHC class I loading [LiteratureReference:983315] The macromolecular peptide-loading complex in MHC class I-dependent antigen presentation [LiteratureReference:983433] Quality control of MHC class I maturation [LiteratureReference:1177545] A transmembrane tail: interaction of tapasin with TAP and the MHC class I molecule [LiteratureReference:1177546] Tapasin enhances MHC class I peptide presentation according to peptide half-life
modified [InstanceEdit:983177] Jupe, S, 2010-10-29 [InstanceEdit:983423] Garapati, P V, 2010-11-01 [InstanceEdit:983434] Garapati, P V, 2010-11-01 [InstanceEdit:985506] Garapati, P V, 2010-11-03 [InstanceEdit:1004532] Garapati, P V, 2010-11-09 [InstanceEdit:1027408] Garapati, P V, 2010-11-18 [InstanceEdit:1093901] Matthews, L, 2010-11-29 [InstanceEdit:1177557] Garapati, P V, 2011-01-26 [InstanceEdit:1213481] Garapati, P V, 2011-02-11 [InstanceEdit:1222763] Garapati, P V, 2011-02-28 [InstanceEdit:1295503] Garapati, P V, 2011-05-16 [InstanceEdit:1307823] Garapati, P V, 2011-05-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9910706] D'Eustachio, Peter, 2024-05-16
name Formation of peptide loading complex (PLC)
output [Complex:983121] MHC:B2M peptide loading complex [endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent
releaseDate 2011-06-14
reviewed [InstanceEdit:1213482] Elliott, T, 2011-02-10
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1357654] R-HSA-983142.3
summation [Summation:982856] Upon interaction of Beta-2-microglobin (B2M) with MHC class ...
(hasEvent) [Pathway:983170] Antigen Presentation: Folding, assembly and peptide loading of class I MHC [Homo sapiens]
(precedingEvent) [Reaction:8951499] Loading of antigenic peptides on to class I MHC [Homo sapiens]
(updatedInstance) [_UpdateTracker:9782123] Update Tracker - [Reaction:983142] Formation of peptide loading complex (PLC) - v59:[modifyText]
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