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Details on Person Transfer of Ub from E2 to substrate and release of E2

Class:Id	Reaction:983140
_displayName	Transfer of Ub from E2 to substrate and release of E2
_doRelease	TRUE
_timestamp	2011-06-10 08:47:08
authored	[InstanceEdit:983164] Garapati, P V, 2010-10-29
catalystActivity	[CatalystActivity:983139] ubiquitin-protein transferase activity of E3 ligases in proteasomal degradation [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:983151] Garapati, P V, 2010-10-29
edited	[InstanceEdit:983164] Garapati, P V, 2010-10-29
input	[SimpleEntity:113592] ATP [cytosol] [Complex:983126] Ag-substrate:E3:E2:Ub [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:982919] A novel family of membrane-bound E3 ubiquitin ligases [LiteratureReference:982903] U-box proteins as a new family of ubiquitin ligases [LiteratureReference:982870] RING domain E3 ubiquitin ligases
modified	[InstanceEdit:1004532] Garapati, P V, 2010-11-09 [InstanceEdit:1027408] Garapati, P V, 2010-11-18 [InstanceEdit:1093901] Matthews, L, 2010-11-29 [InstanceEdit:1177556] Garapati, P V, 2011-01-26 [InstanceEdit:1213481] Garapati, P V, 2011-02-11 [InstanceEdit:1222763] Garapati, P V, 2011-02-28 [InstanceEdit:1295503] Garapati, P V, 2011-05-16 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Transfer of Ub from E2 to substrate and release of E2
output	[SimpleEntity:76577] AMP [cytosol] [CandidateSet:947628] E2 Ubiquitin-conjugating enzyme [cytosol] [Homo sapiens] [Complex:983131] E3:Ub:substrate [cytosol] [Homo sapiens] [SimpleEntity:111294] PPi [cytosol]
precedingEvent	[Reaction:983157] Interaction of E3 with substrate and E2-Ub complex [Homo sapiens] [Reaction:983152] Transfer of ubiquitin from E1 to E2 [Homo sapiens]
releaseDate	2011-06-14
reviewed	[InstanceEdit:1213482] Elliott, T, 2011-02-10
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1357633] R-HSA-983140.2
summation	[Summation:982873] Interaction of E3 with both substrate and E2-Ub, brings them...
(hasEvent)	[Pathway:983168] Antigen processing: Ubiquitination & Proteasome degradation [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:983156] Polyubiquitination of substrate [Homo sapiens]
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No pathways have been reviewed or authored by Transfer of Ub from E2 to substrate and release of E2 (983140)