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Details on Person Transport of MHC heterotrimer to ER exit site

Class:Id	Reaction:983138
_displayName	Transport of MHC heterotrimer to ER exit site
_doRelease	TRUE
_timestamp	2024-05-16 16:48:11
authored	[InstanceEdit:983164] Garapati, P V, 2010-10-29
compartment	[Compartment:5263265] lumenal side of endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:983151] Garapati, P V, 2010-10-29
edited	[InstanceEdit:983164] Garapati, P V, 2010-10-29
input	[Complex:983132] Antigen peptide bound class I MHC:BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:982989] Bap31 enhances the endoplasmic reticulum export and quality control of human class I MHC molecules [LiteratureReference:982998] Interaction of Bap31 and MHC class I molecules and their traffic out of the endoplasmic reticulum [LiteratureReference:983294] Selective export of MHC class I molecules from the ER after their dissociation from TAP [LiteratureReference:983433] Quality control of MHC class I maturation
modified	[InstanceEdit:983423] Garapati, P V, 2010-11-01 [InstanceEdit:983434] Garapati, P V, 2010-11-01 [InstanceEdit:985506] Garapati, P V, 2010-11-03 [InstanceEdit:1004532] Garapati, P V, 2010-11-09 [InstanceEdit:1027408] Garapati, P V, 2010-11-18 [InstanceEdit:1093901] Matthews, L, 2010-11-29 [InstanceEdit:1213481] Garapati, P V, 2011-02-11 [InstanceEdit:1222763] Garapati, P V, 2011-02-28 [InstanceEdit:1295503] Garapati, P V, 2011-05-16 [InstanceEdit:1307823] Garapati, P V, 2011-05-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9910706] D'Eustachio, Peter, 2024-05-16
name	Transport of MHC heterotrimer to ER exit site
output	[Complex:983114] Antigen peptide bound class I MHC [lumenal side of endoplasmic reticulum membrane] [Homo sapiens] [Polymer:983323] BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent	[Reaction:983161] Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex [Homo sapiens] [Reaction:8951499] Loading of antigenic peptides on to class I MHC [Homo sapiens]
releaseDate	2011-06-14
reviewed	[InstanceEdit:1213482] Elliott, T, 2011-02-10
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1357558] R-HSA-983138.3
summation	[Summation:982865] When the loaded peptide is of a sufficiently high-affinity t...
(hasEvent)	[Pathway:983170] Antigen Presentation: Folding, assembly and peptide loading of class I MHC [Homo sapiens]
(precedingEvent)	[Reaction:983426] Capturing cargo and formation of prebudding complex [Homo sapiens] [Reaction:9755328] SARS-CoV-2 8 binds class I MHC [Homo sapiens]
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No pathways have been reviewed or authored by Transport of MHC heterotrimer to ER exit site (983138)