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Details on Person An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

Class:IdLiteratureReference:982896
_displayNameAn IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides
_timestamp2010-10-29 09:30:11
author[Person:982920] Saric, T
[Person:982921] Chang, SC
[Person:982900] Hattori, A
[Person:982863] York, IA
[Person:982985] Markant, S
[Person:873984] Rock, KL
[Person:419417] Tsujimoto, M
[Person:982843] Goldberg, AL
created[InstanceEdit:982973] Garapati, P V, 2010-10-29
journalNat Immunol
pages1169-76
pubMedIdentifier12436109
titleAn IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides
volume3
year2002
(literatureReference)[BlackBoxEvent:983158] Trimming of peptides in ER [Homo sapiens]
[CatalystActivityReference:9643201] endopeptidase activity of ERAP1/2 [endoplasmic reticulum lumen] The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues
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