Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person Transporter associated with antigen processing (TAP) is a he...
| Class:Id | Summation:982881 |
|---|---|
| _displayName | Transporter associated with antigen processing (TAP) is a he... |
| _timestamp | 2024-06-17 18:11:07 |
| created | [InstanceEdit:982858] Garapati, P V, 2010-10-29 |
| modified | [InstanceEdit:983177] Jupe, S, 2010-10-29 [InstanceEdit:9913782] Shamovsky, Veronica, 2024-06-17 |
| text | Transporter associated with antigen processing (TAP) is a heterodimeric complex, composed of TAP1 and TAP2 proteins, members of the ATP-binding cassette (ABC) superfamily. TAP consists of two transmembrane domains (TMDs) and two cytosolic nucleotide-binding domains. Peptide binding to the cytosolic-facing cavity formed by the TMDs causes it to undergo a conformational change that induces ATP hydrolysis, forcing the opening of a pore and translocation of the peptide into the ER lumen. TAP transports peptides in the range of 8-16 amino acids into the ER, which is the peptide length typically generated by the immunoproteasome. |
| (summation) | [Reaction:983144] Transport of Antigen peptide in to ER [Homo sapiens] |
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No pathways have been reviewed or authored by Transporter associated with antigen processing (TAP) is a he... (982881)
