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Details on Person Transcription of respiratory syncytial virus subgenomic positive sense mRNAs

Class:IdBlackBoxEvent:9828639
_displayNameTranscription of respiratory syncytial virus subgenomic positive sense mRNAs
_doReleaseTRUE
_timestamp2023-11-09 15:47:20
authored[InstanceEdit:9828640] Orlic-Milacic, Marija, 2023-02-16
catalystActivity[CatalystActivity:9833932] RNA-directed RNA polymerase activity of RdRP:p-M2-1:hRSV A nucleocapsid [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9828640] Orlic-Milacic, Marija, 2023-02-16
disease[Disease:9833927] respiratory syncytial virus infectious disease
edited[InstanceEdit:9853005] Orlic-Milacic, Marija, 2023-11-09
input[Complex:9833931] RdRP:p-M2-1:hRSV A nucleocapsid [cytosol] [Human respiratory syncytial virus A]
[SimpleEntity:6806881] NTP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9833037] Nucleotide sequences of the 1B and 1C nonstructural protein mRNAs of human respiratory syncytial virus
[LiteratureReference:9832155] Expression and characterisation of the NS1 and NS2 proteins of respiratory syncytial virus
[LiteratureReference:9833098] Construction and characterization of cDNA clones for four respiratory syncytial viral genes
[LiteratureReference:9833146] Nucleotide sequence of the gene encoding respiratory syncytial virus matrix protein
[LiteratureReference:9829048] Respiratory syncytial virus fusion glycoprotein: nucleotide sequence of mRNA, identification of cleavage activation site and amino acid sequence of N-terminus of F1 subunit
[LiteratureReference:9833895] Transcriptional mapping of human respiratory syncytial virus
[LiteratureReference:9833893] Effects of mutations in the gene-start and gene-end sequence motifs on transcription of monocistronic and dicistronic minigenomes of respiratory syncytial virus
[LiteratureReference:9833892] Gene overlap and site-specific attenuation of transcription of the viral polymerase L gene of human respiratory syncytial virus
[LiteratureReference:9833898] Model for polymerase access to the overlapped L gene of respiratory syncytial virus
[LiteratureReference:9834691] Identification of internal sequences in the 3' leader region of human respiratory syncytial virus that enhance transcription and confer replication processivity
[LiteratureReference:9832033] Requirement of cysteines and length of the human respiratory syncytial virus M2-1 protein for protein function and virus viability
[LiteratureReference:9837752] Transcription of human respiratory syncytial virus genome RNA in vitro: requirement of cellular factor(s)
[LiteratureReference:9838528] Analysis of the gene start and gene end signals of human respiratory syncytial virus: quasi-templated initiation at position 1 of the encoded mRNA
[LiteratureReference:9834693] The M2-2 protein of human respiratory syncytial virus is a regulatory factor involved in the balance between RNA replication and transcription
modified[InstanceEdit:9832416] Orlic-Milacic, Marija, 2023-03-30
[InstanceEdit:9833027] Orlic-Milacic, Marija, 2023-04-12
[InstanceEdit:9833038] Orlic-Milacic, Marija, 2023-04-12
[InstanceEdit:9833097] Orlic-Milacic, Marija, 2023-04-13
[InstanceEdit:9833101] Orlic-Milacic, Marija, 2023-04-13
[InstanceEdit:9833148] Orlic-Milacic, Marija, 2023-04-13
[InstanceEdit:9833242] Orlic-Milacic, Marija, 2023-04-14
[InstanceEdit:9833902] Orlic-Milacic, Marija, 2023-05-04
[InstanceEdit:9833929] Orlic-Milacic, Marija, 2023-05-04
[InstanceEdit:9833937] Orlic-Milacic, Marija, 2023-05-04
[InstanceEdit:9834012] Orlic-Milacic, Marija, 2023-05-05
[InstanceEdit:9834776] Orlic-Milacic, Marija, 2023-05-10
[InstanceEdit:9837541] Orlic-Milacic, Marija, 2023-06-16
[InstanceEdit:9837753] Orlic-Milacic, Marija, 2023-06-17
[InstanceEdit:9837754] Orlic-Milacic, Marija, 2023-06-17
[InstanceEdit:9838530] Orlic-Milacic, Marija, 2023-06-22
[InstanceEdit:9838565] Orlic-Milacic, Marija, 2023-06-23
[InstanceEdit:9850763] Orlic-Milacic, Marija, 2023-10-12
[InstanceEdit:9851885] Orlic-Milacic, Marija, 2023-11-01
[InstanceEdit:9852855] Orlic-Milacic, Marija, 2023-11-07
[InstanceEdit:9853009] Orlic-Milacic, Marija, 2023-11-09
nameTranscription of respiratory syncytial virus subgenomic positive sense mRNAs
output[Complex:9834004] hRSV A nascent mRNAs:RdRP:p-M2-1 [cytosol] [Human respiratory syncytial virus A]
precedingEvent
regulatedBy[NegativeRegulation:9834712] Negative regulation by 'M2-2 [cytosol]'
[PositiveRegulation:9837540] Positive regulation by 'HSPA8 [cytosol]'
regulationReference[RegulationReference:9837538] Positive regulation by 'HSPA8 [cytosol]' Interactome analysis of the human respiratory syncytial virus RNA polymerase complex identifies protein chaperones as important cofactors that promote L-protein stability and RNA synthesis
relatedSpecies[Species:9717528] Human respiratory syncytial virus A
releaseDate2023-12-06
reviewed[InstanceEdit:9852848] Bergeron, Harrison Christopher, 2023-11-03
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9828663] R-HSA-9828639.1
summation[Summation:9833036] The RNA-dependent RNA polymerase complex (RdRP) of the human...
(hasEvent)[Pathway:9828642] Respiratory syncytial virus genome transcription [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9830848] L protein acts as a cap N7 methyltransferase to modify RSV mRNAs [Homo sapiens]
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No pathways have been reviewed or authored by Transcription of respiratory syncytial virus subgenomic positive sense mRNAs (9828639)
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