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Details on Person PfHT1 binds Plasmodium HT1 inhibitors

Class:IdReaction:9828299
_displayNamePfHT1 binds Plasmodium HT1 inhibitors
_timestamp2023-02-15 09:39:39
authored[InstanceEdit:9828250] Stephan, Ralf, 2023-02-12
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:9828318] Stephan, Ralf, 2023-02-13
disease[Disease:9660981] malaria
input[DefinedSet:9828316] Plasmodium hexose transporter inhibitors [extracellular region]
[EntityWithAccessionedSequence:9828248] PfHT1 [plasma membrane] [Plasmodium falciparum]
isChimericFALSE
literatureReference[LiteratureReference:9828225] An overview of the Plasmodium falciparum hexose transporter and its therapeutic interventions
[LiteratureReference:9828275] Comparison of effects of green tea catechins on apicomplexan hexose transporters and mammalian orthologues
[LiteratureReference:9828296] Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Screening Focused Libraries of Anti-Malarial Compounds
[LiteratureReference:9828301] Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum
[LiteratureReference:9828303] The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir
[LiteratureReference:9828460] Neither the HIV protease inhibitor lopinavir-ritonavir nor the antimicrobial trimethoprim-sulfamethoxazole prevent malaria relapse in plasmodium cynomolgi-infected non-human primates
[LiteratureReference:9828450] The frequency of malaria is similar among women receiving either lopinavir/ritonavir or nevirapine-based antiretroviral treatment
[LiteratureReference:9828480] Malaria in HIV-Infected Children Receiving HIV Protease-Inhibitor- Compared with Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy, IMPAACT P1068s, Substudy to P1060
[LiteratureReference:9828486] Brief Report: No Differences Between Lopinavir/Ritonavir and Nonnucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy on Clearance of Plasmodium falciparum Subclinical Parasitemia in Adults Living With HIV Starting Treatment (A5297)
[LiteratureReference:9828471] Prevalence of Asymptomatic Parasitemia and Gametocytemia in HIV-Infected Children on Differing Antiretroviral Therapy
modified[InstanceEdit:9828326] Stephan, Ralf, 2023-02-13
[InstanceEdit:9828469] Stephan, Ralf, 2023-02-15
namePfHT1 binds Plasmodium HT1 inhibitors
output[Complex:9828297] Plasmodium HT1 inhbitors:PfHT1 [plasma membrane] [Plasmodium falciparum]
relatedSpecies[Species:170928] Plasmodium falciparum
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9828319] R-HSA-9828299.1
summation[Summation:9828497] The glucose-importing function of Plasmodium falciparum hexo...
(hasEvent)[Pathway:9827931] Hexose transport [Homo sapiens]
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No pathways have been reviewed or authored by PfHT1 binds Plasmodium HT1 inhibitors (9828299)
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