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Details on Person PfHT1 imports hexoses to cytosol

Class:Id	Reaction:9828247
_displayName	PfHT1 imports hexoses to cytosol
_timestamp	2023-02-14 10:19:13
authored	[InstanceEdit:9828229] Stephan, Ralf, 2023-02-11
catalystActivity	[CatalystActivity:9828245] hexose transmembrane transporter activity of PfHT1 [plasma membrane]
compartment	[Compartment:984] extracellular region [Compartment:70101] cytosol
created	[InstanceEdit:9828250] Stephan, Ralf, 2023-02-12
disease	[Disease:9660981] malaria
input	[DefinedSet:9828246] hexose [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:9828225] An overview of the Plasmodium falciparum hexose transporter and its therapeutic interventions [LiteratureReference:9828403] Intraerythrocytic Plasmodium falciparum expresses a high affinity facilitative hexose transporter [LiteratureReference:9828401] Rate of glucose consumption by malarial blood [LiteratureReference:9828413] Validation of the hexose transporter of Plasmodium falciparum as a novel drug target
modified	[InstanceEdit:9828318] Stephan, Ralf, 2023-02-13 [InstanceEdit:9828326] Stephan, Ralf, 2023-02-13 [InstanceEdit:9828402] Stephan, Ralf, 2023-02-14
name	PfHT1 imports hexoses to cytosol
output	[DefinedSet:9828244] hexose [cytosol]
regulatedBy	[NegativeRegulation:9828284] Negative regulation by 'Plasmodium HT1 inhbitors:PfHT1 [plasma membrane]'
regulationReference	[RegulationReference:9828317] Negative regulation by 'Plasmodium HT1 inhbitors:PfHT1 [plasma membrane]' The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir
relatedSpecies	[Species:170928] Plasmodium falciparum
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9828254] R-HSA-9828247.1
summation	[Summation:9828404] Plasmodium falciparum hexose transporter 1 (PfHT1) facilitat...
(hasEvent)	[Pathway:9827931] Hexose transport [Homo sapiens]
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No pathways have been reviewed or authored by PfHT1 imports hexoses to cytosol (9828247)