Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person JAK2 phosphorylation

Class:Id	BlackBoxEvent:982810
_displayName	JAK2 phosphorylation
_doRelease	TRUE
_timestamp	2011-11-23 11:07:33
authored	[InstanceEdit:976955] Jupe, S, 2010-10-14
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:982796] Jupe, S, 2010-10-28
edited	[InstanceEdit:1362504] Jupe, S, 2011-06-10
input	[DefinedSet:1364055] Activated cytokine-like hormone receptors [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:982795] Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase [LiteratureReference:1302675] Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase JAK2
modified	[InstanceEdit:1168383] Jupe, S, 2010-12-20 [InstanceEdit:1168386] Jupe, S, 2010-12-20 [InstanceEdit:1168832] Jupe, S, 2011-01-10 [InstanceEdit:1169139] Jupe, S, 2011-01-12 [InstanceEdit:1169190] Jupe, S, 2011-01-13 [InstanceEdit:1169269] Jupe, S, 2011-01-17 [InstanceEdit:1363242] Jupe, S, 2011-06-13 [InstanceEdit:1364048] Jupe, S, 2011-06-23 [InstanceEdit:1369100] Jupe, S, 2011-07-04 [InstanceEdit:1576229] Jupe, S, 2011-09-07 [InstanceEdit:1671654] Jupe, S, 2011-10-17 [InstanceEdit:1675476] Jupe, S, 2011-10-17 [InstanceEdit:1977950] Jupe, S, 2011-11-08 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	JAK2 phosphorylation
output	[DefinedSet:1364054] Activated cytokine-like hormone receptors, p-Y1007-JAK2 [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[BlackBoxEvent:982768] GH:GHR:JAK2 complex undergoes a conformational change [Homo sapiens] [Reaction:982778] Growth hormone binds the growth hormone receptor [Homo sapiens] [BlackBoxEvent:1671687] PRLR activation [Homo sapiens] [Reaction:976991] Prolactin receptor ligands bind the prolactin receptor [Homo sapiens]
regulatedBy	[PositiveRegulation:1675485] Positive regulation by 'PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane]'
releaseDate	2011-09-20
reviewed	[InstanceEdit:1363241] Herington, AC, 2011-06-13 [InstanceEdit:1364056] Waters, MJ, 2011-06-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1591292] R-HSA-982810.3
summation	[Summation:1168389] Similar models explain JAK activation by the cytokine-like h...
(hasEvent)	[Pathway:982772] Growth hormone receptor signaling [Homo sapiens] [Pathway:1170546] Prolactin receptor signaling [Homo sapiens]
(precedingEvent)	[Reaction:982807] JAK2 phosphorylation of GHR [Homo sapiens] [Reaction:1168423] JAK2 phosphorylation of IRS-1/2 [Homo sapiens] [Reaction:1168768] JAK2 binds STAT1/3 [Homo sapiens] [BlackBoxEvent:1364043] Tyrosine phosphorylation of PRLR [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9788896] Update Tracker - [BlackBoxEvent:982810] JAK2 phosphorylation - v39:[addLiteratureReference, addRegulator, modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by JAK2 phosphorylation (982810)