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Details on Person Expression of CXCR4 in primordial germ cells

Class:Id	BlackBoxEvent:9828028
_displayName	Expression of CXCR4 in primordial germ cells
_doRelease	TRUE
_timestamp	2023-05-09 02:19:05
authored	[InstanceEdit:9828007] May, Bruce, 2023-02-09
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:9828025] May, Bruce, 2023-02-09
edited	[InstanceEdit:9828007] May, Bruce, 2023-02-09
input	[EntityWithAccessionedSequence:8960723] CXCR4 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9827861] Sequential enhancer state remodelling defines human germline competence and specification [LiteratureReference:9828776] Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells
modified	[InstanceEdit:9828785] May, Bruce, 2023-02-17 [InstanceEdit:9833798] May, Bruce, 2023-05-03 [InstanceEdit:9834660] May, Bruce, 2023-05-09 [InstanceEdit:9835794] Matthews, Lisa, 2023-05-17
name	Expression of CXCR4 in primordial germ cells
output	[EntityWithAccessionedSequence:2980772] CXCR4 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9828034] SOX17 binds the CXCR4 gene [Homo sapiens] [BlackBoxEvent:9828100] Expression of SOX17 in primordial germ cells [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9828031] Positive gene expression regulation by 'SOX17:CXCR4 gene [nucleoplasm]'
regulationReference	[RegulationReference:9828017] Positive gene expression regulation by 'SOX17:CXCR4 gene [nucleoplasm]' Sequential enhancer state remodelling defines human germline competence and specification
releaseDate	2023-06-07
reviewed	[InstanceEdit:9833796] Tam, Patrick P L, 2023-05-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9828046] R-HSA-9828028.1
summation	[Summation:9828757] Human PGCs express CXCR4 on their cell membranes (Mishra et ...
(hasEvent)	[Pathway:9827857] Specification of primordial germ cells [Homo sapiens]
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