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Details on Person Growth hormone binds the growth hormone receptor

Class:Id	Reaction:982778
_displayName	Growth hormone binds the growth hormone receptor
_doRelease	TRUE
_timestamp	2011-09-09 08:56:40
authored	[InstanceEdit:976955] Jupe, S, 2010-10-14
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:982796] Jupe, S, 2010-10-28
edited	[InstanceEdit:1362504] Jupe, S, 2011-06-10
input	[Complex:982764] Growth Hormone Receptor-JAK2 dimer [plasma membrane] [Homo sapiens] [DefinedSet:982814] Growth Hormone [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:982767] Human growth hormone and extracellular domain of its receptor: crystal structure of the complex
modified	[InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:1168344] Jupe, S, 2010-12-17 [InstanceEdit:1169269] Jupe, S, 2011-01-17 [InstanceEdit:1362469] Jupe, S, 2011-06-10 [InstanceEdit:1363242] Jupe, S, 2011-06-13 [InstanceEdit:1364048] Jupe, S, 2011-06-23 [InstanceEdit:1576229] Jupe, S, 2011-09-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Growth hormone binds the growth hormone receptor
output	[Complex:982813] Growth Hormone: Growth Hormone Receptor-JAK2 dimer [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:982775] Growth hormone receptor dimerizes [Homo sapiens] [Reaction:982792] Growth hormone receptor binds JAK2 [Homo sapiens]
releaseDate	2011-09-20
reviewed	[InstanceEdit:1363241] Herington, AC, 2011-06-13 [InstanceEdit:1364056] Waters, MJ, 2011-06-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1591269] R-HSA-982778.2
summation	[Summation:982781] The growth hormone receptor (GHR) belongs to the superfamily...
(hasEvent)	[Pathway:982772] Growth hormone receptor signaling [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:982768] GH:GHR:JAK2 complex undergoes a conformational change [Homo sapiens] [Reaction:1168456] Growth hormone receptor binds Lyn [Homo sapiens]
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No pathways have been reviewed or authored by Growth hormone binds the growth hormone receptor (982778)