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Details on Person p-S742 TBX3 binds ID1 promoter

Class:IdReaction:9825776
_displayNamep-S742 TBX3 binds ID1 promoter
_doReleaseTRUE
_timestamp2024-11-08 15:59:11
authored[InstanceEdit:9825798] Rothfels, Karen, 2023-01-26
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9825775] Rothfels, Karen, 2023-01-26
edited[InstanceEdit:9825798] Rothfels, Karen, 2023-01-26
input[EntityWithAccessionedSequence:9613373] ID1 Gene [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:9825680] p-S742 TBX3 [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17
isChimericFALSE
literatureReference[LiteratureReference:9825509] TBX3 Promotes Melanoma Migration by Transcriptional Activation of ID1, which Prevents Activation of E-Cadherin by MITF
[LiteratureReference:9613399] Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms
[LiteratureReference:9613409] Id family of helix-loop-helix proteins in cancer
[LiteratureReference:9613471] Id proteins: small molecules, mighty regulators
[LiteratureReference:9768551] The microphthalmia transcription factor (MITF) contains two N-terminal domains required for transactivation of osteoclast target promoters and rescue of mi mutant osteoclasts
[LiteratureReference:9917238] Epigenetic regulation during melanocyte development and homeostasis
[LiteratureReference:9825476] Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation
modified[InstanceEdit:9854922] Rothfels, Karen, 2023-11-28
[InstanceEdit:9859417] Rothfels, Karen, 2024-01-19
[InstanceEdit:9863246] Rothfels, Karen, 2024-02-28
[InstanceEdit:9907153] Rothfels, Karen, 2024-04-04
[InstanceEdit:9909022] Rothfels, Karen, 2024-04-25
[InstanceEdit:9910861] Rothfels, Karen, 2024-05-21
[InstanceEdit:9917237] Rothfels, Karen, 2024-08-01
[InstanceEdit:9927682] Rothfels, Karen, 2024-11-08
namep-S742 TBX3 binds ID1 promoter
output[Complex:9825708] p-S742 TBX3:ID1 gene [nucleoplasm] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2024-06-15
reviewed[InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21
[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05
[InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9825778] R-HSA-9825776.3
summation[Summation:9825694] AKT3-phosphorylated TBX3 binds to the promoter of ID1 to act...
(hasEvent)[Pathway:9856649] Transcriptional and post-translational regulation of MITF-M expression and activity [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9825774] SNAI2 and TBX3 repress CDH1 gene expression during melanocyte development [Homo sapiens]
[BlackBoxEvent:9825780] TBX3-dependent ID1 gene expression [Homo sapiens]
(updatedInstance)[_UpdateTracker:9919485] Update Tracker - [Reaction:9825776] p-S742 TBX3 binds ID1 promoter - v90:[modifyText, removeLiteratureReference]
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No pathways have been reviewed or authored by p-S742 TBX3 binds ID1 promoter (9825776)
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