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Details on Person SNAI2 and TBX3 repress CDH1 gene expression during melanocyte development
Class:Id BlackBoxEvent:9825774 _displayName SNAI2 and TBX3 repress CDH1 gene expression during melanocyte development _doRelease TRUE _timestamp 2024-11-08 15:58:39 authored [InstanceEdit:9825798] Rothfels, Karen, 2023-01-26 compartment [Compartment:7660] nucleoplasm [Compartment:876] plasma membrane created [InstanceEdit:9825775] Rothfels, Karen, 2023-01-26 edited [InstanceEdit:9825798] Rothfels, Karen, 2023-01-26 input [EntityWithAccessionedSequence:9756422] CDH1 gene [nucleoplasm] [Homo sapiens] internalReviewed [InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17 [InstanceEdit:9865964] Orlic-Milacic, Marija, 2024-03-20 literatureReference [LiteratureReference:9825360] N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells [LiteratureReference:9825374] The melanocyte differentiation program predisposes to metastasis after neoplastic transformation [LiteratureReference:9825366] Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration [LiteratureReference:9730389] The melanocyte lineage in development and disease [LiteratureReference:9756421] The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression [LiteratureReference:9730375] Melanocytes in development, regeneration, and cancer [LiteratureReference:9857452] Calreticulin represses E-cadherin gene expression in Madin-Darby canine kidney cells via Slug [LiteratureReference:9857455] SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by snail and slug: a potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma [LiteratureReference:9768562] The SLUG zinc-finger protein represses E-cadherin in breast cancer [LiteratureReference:9857311] Role of T-box genes in cancer, epithelial-mesenchymal transition, and cancer stem cells [LiteratureReference:9768259] Tbx3 represses E-cadherin expression and enhances melanoma invasiveness [LiteratureReference:9825391] Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression modified [InstanceEdit:9854922] Rothfels, Karen, 2023-11-28 [InstanceEdit:9857459] Rothfels, Karen, 2024-01-04 [InstanceEdit:9863248] Rothfels, Karen, 2024-02-28 [InstanceEdit:9863252] Rothfels, Karen, 2024-02-28 [InstanceEdit:9907153] Rothfels, Karen, 2024-04-04 [InstanceEdit:9909022] Rothfels, Karen, 2024-04-25 [InstanceEdit:9910861] Rothfels, Karen, 2024-05-21 [InstanceEdit:9927682] Rothfels, Karen, 2024-11-08 name SNAI2 and TBX3 repress CDH1 gene expression during melanocyte development output [EntityWithAccessionedSequence:198003] CDH1(155-882) [plasma membrane] [Homo sapiens] precedingEvent
previousReviewStatus [ReviewStatus:9821383] three stars regulatedBy [NegativeGeneExpressionRegulation:9796544] Negative gene expression regulation by 'SNAI2:CDH1 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:9825739] Negative gene expression regulation by 'p-S742 TBX3:CDH1 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:9907128] Negative gene expression regulation by 'EDN1, EDN3:EDNRB [plasma membrane]' regulationReference [RegulationReference:9825763] Negative gene expression regulation by 'CDH1 gene:p-S742 TBX3 [nucleoplasm]' Tbx3 represses E-cadherin expression and enhances melanoma invasiveness [RegulationReference:9907137] Negative gene expression regulation by 'SNAI2:CDH1 gene [nucleoplasm]' SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by snail and slug: a potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma [RegulationReference:9907134] Negative gene expression regulation by 'EDN1, EDN3:EDNRB [plasma membrane]' Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression releaseDate 2024-06-15 reviewed [InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21 [InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:9825777] R-HSA-9825774.2 structureModified [InstanceEdit:9907153] Rothfels, Karen, 2024-04-04 summation [Summation:9857457] Changes in relative levels of E- and N-cadherin contribute t... (hasEvent) [Pathway:9856649] Transcriptional and post-translational regulation of MITF-M expression and activity [Homo sapiens]
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