Query author contributions in Reactome
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Details on Person SNAI2, also known as SLUG or SNAIL2, is a DNA-binding zinc f...
| Class:Id | Summation:9825399 |
|---|---|
| _displayName | SNAI2, also known as SLUG or SNAIL2, is a DNA-binding zinc f... |
| _timestamp | 2024-04-04 16:23:16 |
| created | [InstanceEdit:9825398] Rothfels, Karen, 2023-01-26 |
| modified | [InstanceEdit:9859417] Rothfels, Karen, 2024-01-19 [InstanceEdit:9907117] Rothfels, Karen, 2024-04-04 |
| text | SNAI2, also known as SLUG or SNAIL2, is a DNA-binding zinc finger transcriptional factor with roles in cellular differentiation, DNA damage repair, tumorigenesis and epithelial-mesenchymal transition (reviewed in Zhou et al, 2019). SNAI2 contributes to cell migration by repressing CDH1 (E-cadherin) (Poser et al, 2001; Li et al, 2001; Gupta et al, 2005; Bagnato et al, 2004; reviewed in Zhou et al, 2019). Changes in relative levels of E- and N-cadherin contribute to migration of neural crest cells during melanocyte differentiation, and also play a role during the development of melanoma (Li et al, 2001; Gupta et al, 2005; LaBonne et al, 2000; reviewed in Mort et al, 2015). |
| (summation) | [BlackBoxEvent:9825406] SNAI2 gene expression [Homo sapiens] |
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No pathways have been reviewed or authored by SNAI2, also known as SLUG or SNAIL2, is a DNA-binding zinc f... (9825399)
