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Details on Person MSGN1 binds and activates transcription of the DLL3 gene in ...
| Class:Id | Summation:9825282 |
|---|---|
| _displayName | MSGN1 binds and activates transcription of the DLL3 gene in ... |
| _timestamp | 2023-02-02 17:45:34 |
| created | [InstanceEdit:9825318] May, Bruce, 2023-01-25 |
| literatureReference | [LiteratureReference:9825914] Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock |
| modified | [InstanceEdit:9827742] May, Bruce, 2023-02-01 [InstanceEdit:9827744] May, Bruce, 2023-02-02 [InstanceEdit:9827751] May, Bruce, 2023-02-02 |
| text | MSGN1 binds and activates transcription of the DLL3 gene in presomitic mesoderm (inferred from mouse homologs). DLL3 is a ligand of NOTCH that is normally inhibitory, however, in mice, loss of Dll3 in presomitic mesoderm paradoxically causes a reduction in Notch signaling (Bochter et al. 2022). |
| (summation) | [BlackBoxEvent:9825306] Expression of DLL3 in presomitic mesoderm [Homo sapiens] |
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No pathways have been reviewed or authored by MSGN1 binds and activates transcription of the DLL3 gene in ... (9825282)
