Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person TLR7(?-1049) Y264H [endolysosome membrane]

Class:IdEntityWithAccessionedSequence:9824828
_displayNameTLR7(?-1049) Y264H [endolysosome membrane]
_timestamp2023-01-23 00:46:34
compartment[Compartment:1660541] endolysosome membrane
created[InstanceEdit:9824838] Shamovsky, Veronica, 2023-01-23
disease[Disease:9629266] autoimmune hypersensitivity disease
[Disease:9625952] systemic lupus erythematosus
endCoordinate1049
hasModifiedResidue[ReplacedResidue:9824824] L-tyrosine 264 replaced with L-histidine
literatureReference[LiteratureReference:9824739] TLR7 gain-of-function genetic variation causes human lupus
nameTLR7(?-1049) Y264H
TLR7 Y264H C-term fragment
processed TLR7 Y264H
Toll Like Receptor 7 (TLR 7)
referenceEntity[ReferenceGeneProduct:188133] UniProt:Q9NYK1 TLR7 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9824858] R-HSA-9824828.1
(hasComponent)[Complex:9824826] C-ter TLR7 Y264H dimer [endolysosome membrane] [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by TLR7(?-1049) Y264H [endolysosome membrane] (9824828)