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Details on Person p-S133-CREB1 binds MITF promoter

Class:IdReaction:9824653
_displayNamep-S133-CREB1 binds MITF promoter
_doReleaseTRUE
_timestamp2024-11-08 15:59:00
authored[InstanceEdit:9825798] Rothfels, Karen, 2023-01-26
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9824655] Rothfels, Karen, 2023-01-21
edited[InstanceEdit:9825798] Rothfels, Karen, 2023-01-26
input[EntityWithAccessionedSequence:9730399] MITF gene [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:111910] p-S133-CREB1 [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17
isChimericFALSE
literatureReference[LiteratureReference:9824637] Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes
[LiteratureReference:9824648] alpha-Melanocyte-stimulating hormone signaling regulates expression of microphthalmia, a gene deficient in Waardenburg syndrome
[LiteratureReference:9854804] A tissue-restricted cAMP transcriptional response: SOX10 modulates alpha-melanocyte-stimulating hormone-triggered expression of microphthalmia-associated transcription factor in melanocytes
modified[InstanceEdit:9825009] Rothfels, Karen, 2023-01-23
[InstanceEdit:9854922] Rothfels, Karen, 2023-11-28
[InstanceEdit:9857438] Orlic-Milacic, Marija, 2024-01-04
[InstanceEdit:9863246] Rothfels, Karen, 2024-02-28
[InstanceEdit:9910861] Rothfels, Karen, 2024-05-21
[InstanceEdit:9927682] Rothfels, Karen, 2024-11-08
namep-S133-CREB1 binds MITF promoter
output[Complex:9824649] p-S133-CREB1:MITF gene [nucleoplasm] [Homo sapiens]
previousReviewStatus[ReviewStatus:9821383] three stars
regulatedBy[PositiveRegulation:9824654] Positive regulation by 'MSH:Melanocortin receptors [plasma membrane]'
regulationReference[RegulationReference:9824652] Positive regulation by 'MSH:Melanocortin receptors [plasma membrane]' Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes
releaseDate2024-03-27
reviewed[InstanceEdit:9863245] Arnheiter, Heinz, 2024-02-26
[InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21
[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05
[InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9824656] R-HSA-9824653.3
summation[Summation:9824631] Alpha-melanocyte-stimulating hormone (alpha MSH) stimulates ...
(hasEvent)[Pathway:9856649] Transcriptional and post-translational regulation of MITF-M expression and activity [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9730412] MITF gene expression [Homo sapiens]
(updatedInstance)[_UpdateTracker:9919384] Update Tracker - [Reaction:9824653] p-S133-CREB1 binds MITF promoter - v90:[modifyText]
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