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Details on Person p-S133-CREB1 binds MITF promoter
Class:Id Reaction:9824653
_displayName p-S133-CREB1 binds MITF promoter
_doRelease TRUE
_timestamp 2024-11-08 15:59:00
authored [InstanceEdit:9825798] Rothfels, Karen, 2023-01-26
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:9824655] Rothfels, Karen, 2023-01-21
edited [InstanceEdit:9825798] Rothfels, Karen, 2023-01-26
input [EntityWithAccessionedSequence:9730399] MITF gene [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:111910] p-S133-CREB1 [nucleoplasm] [Homo sapiens]
internalReviewed [InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17
isChimeric FALSE
literatureReference [LiteratureReference:9824637] Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes [LiteratureReference:9824648] alpha-Melanocyte-stimulating hormone signaling regulates expression of microphthalmia, a gene deficient in Waardenburg syndrome [LiteratureReference:9854804] A tissue-restricted cAMP transcriptional response: SOX10 modulates alpha-melanocyte-stimulating hormone-triggered expression of microphthalmia-associated transcription factor in melanocytes
modified [InstanceEdit:9825009] Rothfels, Karen, 2023-01-23 [InstanceEdit:9854922] Rothfels, Karen, 2023-11-28 [InstanceEdit:9857438] Orlic-Milacic, Marija, 2024-01-04 [InstanceEdit:9863246] Rothfels, Karen, 2024-02-28 [InstanceEdit:9910861] Rothfels, Karen, 2024-05-21 [InstanceEdit:9927682] Rothfels, Karen, 2024-11-08
name p-S133-CREB1 binds MITF promoter
output [Complex:9824649] p-S133-CREB1:MITF gene [nucleoplasm] [Homo sapiens]
previousReviewStatus [ReviewStatus:9821383] three stars
regulatedBy [PositiveRegulation:9824654] Positive regulation by 'MSH:Melanocortin receptors [plasma membrane]'
regulationReference [RegulationReference:9824652] Positive regulation by 'MSH:Melanocortin receptors [plasma membrane]' Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes
releaseDate 2024-03-27
reviewed [InstanceEdit:9863245] Arnheiter, Heinz, 2024-02-26 [InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21 [InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9824656] R-HSA-9824653.3
summation [Summation:9824631] Alpha-melanocyte-stimulating hormone (alpha MSH) stimulates ...
(hasEvent) [Pathway:9856649] Transcriptional and post-translational regulation of MITF-M expression and activity [Homo sapiens]
(precedingEvent) [BlackBoxEvent:9730412] MITF gene expression [Homo sapiens]
(updatedInstance) [_UpdateTracker:9919384] Update Tracker - [Reaction:9824653] p-S133-CREB1 binds MITF promoter - v90:[modifyText]
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