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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person Diagram of Somitogenesis

Class:IdPathwayDiagram:9824474
_displayNameDiagram of Somitogenesis
_timestamp2023-05-10 18:54:10
created[InstanceEdit:9824470] May, Bruce, 2023-01-20
height1197
modified[InstanceEdit:9825334] May, Bruce, 2023-01-25
[InstanceEdit:9825931] May, Bruce, 2023-01-27
[InstanceEdit:9827632] May, Bruce, 2023-01-31
[InstanceEdit:9827742] May, Bruce, 2023-02-01
[InstanceEdit:9834683] May, Bruce, 2023-05-10
[InstanceEdit:9834877] May, Bruce, 2023-05-10
representedPathway[Pathway:9824272] Somitogenesis [Homo sapiens]
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<Component id="51" /> <Component id="60" /> <Component id="62" /> <Component id="63" /> <Component id="64" /> <Component id="65" /> <Component id="66" /> <Component id="76" /> <Component id="77" /> <Component id="78" /> <Component id="88" /> <Component id="89" /> <Component id="90" /> <Component id="91" /> <Component id="92" /> <Component id="93" /> <Component id="95" /> <Component id="96" /> <Component id="97" /> <Component id="98" /> <Component id="100" /> <Component id="101" /> <Component id="99" /> <Component id="102" /> <Component id="21" /> <Component id="43" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableGene id="11" reactomeId="1911481" position="119 129" bounds="74 97 91 65" textPosition="74 124"> <Properties> <displayName>NOTCH1 gene</displayName> </Properties> </org.gk.render.RenderableGene> <org.gk.render.RenderableProtein id="12" reactomeId="9793376" position="477 94" bounds="433 81 89 26" textPosition="451 83"> <Properties> <displayName>MSGN1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="13" reactomeId="9824210" position="266 211" bounds="219 192 95 38" textPosition="221 194" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>MSGN1:NOTCH1 gene</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="15" reactomeId="157024" position="167 1010" bounds="116 996 103 29" textPosition="128 999"> <Properties> <displayName>Pre-NOTCH1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableCompartment id="16" reactomeId="70101" position="676 601" bounds="4 14 1345 1174" textPosition="20 1123" bgColor="250 240 240" lineColor="255 153 102" insets="14 24 1323 1150"> <Properties> <displayName>cytosol</displayName> </Properties> <Components> <Component id="1" /> <Component id="17" /> <Component id="94" /> <Component id="105" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableCompartment id="17" reactomeId="17957" position="397 1051" bounds="89 998 617 106" textPosition="119 1053" bgColor="250 240 240" lineColor="255 153 102" insets="101 1036 598 53"> <Properties> <displayName>endoplasmic reticulum lumen</displayName> </Properties> <Components> <Component id="15" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableGene id="19" reactomeId="9023392" position="255 298" bounds="213 273 84 51" textPosition="220 300"> <Properties> <displayName>DLL1 gene</displayName> </Properties> </org.gk.render.RenderableGene> <org.gk.render.RenderableComplex id="20" reactomeId="9735197" position="541 169" bounds="489 157 104 25" textPosition="497 160" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>LEF1:CTNNB1</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="21" reactomeId="9824208" position="387 372" bounds="325 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bounds="834 340 50 26" textPosition="840 342"> <Properties> <displayName>DLL3</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="40" reactomeId="157939" position="1018 526" bounds="989 514 58 24" textPosition="995 515"> <Properties> <displayName>NICD1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="41" reactomeId="3008668" position="970 496" bounds="943 482 54 28" textPosition="954 485"> <Properties> <displayName>RBPJ</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableGene id="42" reactomeId="9824257" position="895 586" bounds="858 561 75 51" textPosition="860 588"> <Properties> <displayName>HES7 gene</displayName> </Properties> </org.gk.render.RenderableGene> <org.gk.render.RenderableProtein id="43" reactomeId="9793377" position="550 383" bounds="525 368 51 30" textPosition="531 372"> <Properties> <displayName>TBX6</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="44" reactomeId="9824263" position="1047 633" bounds="975 613 145 40" textPosition="977 617" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>LEF1:CTNNB1:TBX6:RBPJ:NICD1:HES7 gene</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="46" reactomeId="9824218" position="944 819" bounds="916 805 57 28" textPosition="925 808"> <Properties> <displayName>HES7</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="47" reactomeId="9824276" position="1053 756" bounds="967 736 173 40" textPosition="974 740" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>HES7:LEF1:CTNNB1:TBX6:RBPJ:NICD1:HES7 gene</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="49" reactomeId="9824247" position="1091 88" bounds="1046 75 90 27" textPosition="1054 80" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>RBPJ:NICD1</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableGene id="50" reactomeId="9824259" position="1197 142" bounds="1159 117 77 51" textPosition="1161 144"> <Properties> <displayName>LFNG gene</displayName> </Properties> </org.gk.render.RenderableGene> <org.gk.render.RenderableComplex id="51" reactomeId="9824201" position="1176 282" bounds="1115 261 123 43" textPosition="1116 268" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>RBPJ:NICD1:MSGN1:LFNG gene</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="61" reactomeId="1460372" position="1263 1025" bounds="1237 1010 53 30" textPosition="1244 1014"> <Properties> <displayName>LFNG</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="62" reactomeId="9824195" position="1184 428" bounds="1132 404 104 48" textPosition="1135 402" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>HES7:RBPJ:NICD1:MSGN1:LFNG gene</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableGene id="77" reactomeId="9793872" position="244 677" bounds="207 652 75 51" textPosition="219 679"> <Properties> <displayName>MESP2 gene</displayName> </Properties> </org.gk.render.RenderableGene> <org.gk.render.RenderableComplex id="78" reactomeId="9793894" position="420 719" bounds="360 707 120 25" textPosition="363 710" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>TBX6:MESP2 gene</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="89" reactomeId="9793805" position="339 803" bounds="307 790 65 26" textPosition="316 792"> <Properties> <displayName>MESP2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableGene id="91" reactomeId="9825609" position="438 893" bounds="401 868 75 51" textPosition="413 895"> <Properties> <displayName>EPHA4 gene</displayName> </Properties> </org.gk.render.RenderableGene> <org.gk.render.RenderableComplex id="92" reactomeId="9825616" position="783 869" bounds="720 857 127 24" textPosition="723 859" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>MESP2:EPHA4 gene</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="94" reactomeId="2682325" position="785 1176" bounds="756 1163 58 26" textPosition="762 1165"> <Properties> <displayName>EPHA4</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableGene id="96" reactomeId="9825594" position="539 747" bounds="498 722 82 51" textPosition="511 749"> <Properties> <displayName>RIPPLY2 gene</displayName> </Properties> </org.gk.render.RenderableGene> <org.gk.render.RenderableComplex id="97" reactomeId="9825557" position="771 795" bounds="697 782 149 27" textPosition="708 787" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>MESP2:RIPPLY2 gene</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="99" reactomeId="9825566" position="583 604" bounds="545 591 76 27" textPosition="557 593"> <Properties> <displayName>RIPPLY2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="101" reactomeId="9825558" position="741 587" bounds="684 568 114 38" textPosition="683 570" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>TBX6:RIPPLY2:26S proteasome</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="102" reactomeId="177750" position="571 485" bounds="515 473 112 24" textPosition="518 475" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>26S proteasome</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableCompartment id="105" reactomeId="17963" position="1170 1073" bounds="1038 1011 264 124" textPosition="1083 1070" bgColor="250 240 240" lineColor="255 153 102" insets="1066 1045 186 64"> <Components> <Component id="61" /> </Components> </org.gk.render.RenderableCompartment> </Nodes> <Edges> <org.gk.render.RenderableReaction id="10" reactomeId="9824216" points="260 126, 263 165, 264 189" position="263 165" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="11" points="174 99" /> <Input id="12" points="430 100" /> </Inputs> <Outputs> <Output id="13" /> </Outputs> <Properties> <displayName>MSGN1 binds the NOTCH1 gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="14" reactomeId="9824219" points="174 99, 174 218, 167 993" position="174 218" lineWidth="1.0" reactionType="Uncertain Process"> <Inputs> <Input id="11" /> </Inputs> <Outputs> <Output id="15" /> </Outputs> <Activators> <Activator id="13" points="216 214" /> </Activators> <Properties> <displayName>Expression of NOTCH1 in paraxial mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="18" reactomeId="9824236" points="398 287, 397 323, 390 351" position="397 323" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="19" points="306 275" /> <Input id="20" points="525 185" /> <Input id="12" points="471 110" /> </Inputs> <Outputs> <Output id="21" /> </Outputs> <Properties> <displayName>MSGN1 and LEF1:CTNNB1 bind the DLL1 gene in presomitic mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="34" reactomeId="9824280" points="889 186, 920 206, 947 226" position="920 206" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="35" points="855 190" /> <Input id="12" points="525 103" /> </Inputs> <Outputs> <Output id="36" /> </Outputs> <Properties> <displayName>MSGN1 binds the DLL3 gene in presomitic mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="39" reactomeId="9824266" points="983 553, 1006 575, 1032 610" position="1006 575" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="40" points="1002 541" /> <Input id="41" points="973 513" /> <Input id="42" points="942 563" /> <Input id="20" points="555 185" /> <Input id="43" points="579 393" /> </Inputs> <Outputs> <Output id="44" /> </Outputs> <Properties> <displayName>LEF1:CTNNB1, NICD1 (NOTCH1) and TBX6 bind the HES7 gene in presomitic mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="45" reactomeId="9824268" points="942 563, 941 684, 943 802" position="941 684" lineWidth="1.0" reactionType="Uncertain Process"> <Inputs> <Input id="42" /> </Inputs> <Outputs> <Output id="46" /> </Outputs> <Inhibitors> <Inhibitor id="47" points="1021 733" /> </Inhibitors> <Activators> <Activator id="44" points="1005 656" /> </Activators> <Properties> <displayName>Expression of HES7 in presomitic mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="48" reactomeId="9824182" points="1141 132, 1157 207, 1170 258" position="1157 207" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="49" points="1106 105" /> <Input id="50" points="1245 119" /> <Input id="12" points="525 96" /> </Inputs> <Outputs> <Output id="51" /> </Outputs> <Properties> <displayName>RBPJ:NICD1 and MSGN1 bind the LFNG gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="60" reactomeId="9824181" points="1245 119, 1268 429, 1263 1007" position="1268 429" lineWidth="1.0" reactionType="Uncertain Process"> <Inputs> <Input id="50" /> </Inputs> <Outputs> <Output id="61" /> </Outputs> <Inhibitors> <Inhibitor id="62" points="1239 428" /> </Inhibitors> <Activators> <Activator id="51" points="1189 307" /> </Activators> <Properties> <displayName>Expression of LFNG in presomitic mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="63" reactomeId="9824222" points="1048 681, 1048 713, 1050 733" position="1048 713" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="44" points="1047 656" /> <Input id="46" points="976 817, 1183 803, 1182 682" /> </Inputs> <Outputs> <Output id="47" /> </Outputs> <Properties> <displayName>HES7 binds the HES7 gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="64" reactomeId="9824196" points="1183 352, 1181 377, 1182 401" position="1181 377" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="46" points="976 818, 1195 813, 1194 610, 1096 464, 1094 350" /> <Input id="51" points="1178 307" /> </Inputs> <Outputs> <Output id="62" /> </Outputs> <Properties> <displayName>HES7 binds the LFNG gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="65" reactomeId="9825275" points="306 275, 308 409, 309 506" position="308 409" lineWidth="1.0" reactionType="Uncertain Process"> <Inputs> <Input id="19" /> </Inputs> <Outputs> <Output id="31" /> </Outputs> <Activators> <Activator id="21" points="348 393" /> </Activators> <Properties> <displayName>Expression of DLL1 in presomitic mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="66" reactomeId="9825306" points="855 190, 858 290, 858 337" position="858 290" lineWidth="1.0" reactionType="Uncertain Process"> <Inputs> <Input id="35" /> </Inputs> <Outputs> <Output id="38" /> </Outputs> <Activators> <Activator id="36" points="930 262" /> </Activators> <Properties> <displayName>Expression of DLL3 in presomitic mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="76" reactomeId="9793837" points="376 645, 396 675, 413 704" position="396 675" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="43" points="540 401" /> <Input id="77" points="291 654" /> </Inputs> <Outputs> <Output id="78" /> </Outputs> <Properties> <displayName>TBX6 binds the MESP2 gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="88" reactomeId="9793933" points="291 654, 319 724, 335 787" position="319 724" lineWidth="1.0" reactionType="Uncertain Process"> <Inputs> <Input id="77" /> </Inputs> <Outputs> <Output id="89" /> </Outputs> <Activators> <Activator id="78" points="357 721" /> </Activators> <Properties> <displayName>Expression of MESP2 in presomitic mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="90" reactomeId="9825564" points="570 859, 622 866, 717 867" position="622 866" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="91" points="485 870" /> <Input id="89" points="375 810" /> </Inputs> <Outputs> <Output id="92" /> </Outputs> <Properties> <displayName>MESP2 binds the EPHA4 gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="93" reactomeId="9825582" points="485 870, 788 939, 785 1160" position="788 939" lineWidth="1.0" reactionType="Uncertain Process"> <Inputs> <Input id="91" /> </Inputs> <Outputs> <Output id="94" /> </Outputs> <Activators> <Activator id="92" points="783 884" /> </Activators> <Properties> <displayName>Expression of EPHA4 in presomitic mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="95" reactomeId="9825631" points="631 801, 660 799, 694 797" position="660 799" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="96" points="589 724" /> <Input id="89" points="375 802" /> </Inputs> <Outputs> <Output id="97" /> </Outputs> <Properties> <displayName>MESP2 binds the RIPPLY2 gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="98" reactomeId="9825615" points="589 724, 585 677, 583 621" position="585 677" lineWidth="1.0" reactionType="Uncertain Process"> <Inputs> <Input id="96" /> </Inputs> <Outputs> <Output id="99" /> </Outputs> <Activators> <Activator id="97" points="749 779" /> </Activators> <Properties> <displayName>Expression of RIPPLY2 in presomitic mesoderm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="100" reactomeId="9825555" points="655 480, 687 518, 726 565" position="687 518" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="102" points="630 481" /> <Input id="99" points="590 588" /> <Input id="43" points="566 401" /> </Inputs> <Outputs> <Output id="101" /> </Outputs> <Properties> <displayName>RIPPLY2 binds TBX6 and recruits the 26S proteasome</displayName> </Properties> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process>
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