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Details on Person The Notch1 intracellular domain (Nicd from Notch signaling) ...
| Class:Id | Summation:9824274 |
|---|---|
| _displayName | The Notch1 intracellular domain (Nicd from Notch signaling) ... |
| _timestamp | 2023-02-02 16:43:39 |
| created | [InstanceEdit:9824212] May, Bruce, 2023-01-18 |
| modified | [InstanceEdit:9825334] May, Bruce, 2023-01-25 [InstanceEdit:9827742] May, Bruce, 2023-02-01 [InstanceEdit:9827744] May, Bruce, 2023-02-02 |
| text | The Notch1 intracellular domain (Nicd from Notch signaling) bound to Rbpj (Bessho et al. 2001), Lef1:Ctnnb1 from Wnt signaling (González et al. 2013), and Tbx6 (González et al. 2013) activate expression of the transcription repressor Hes7 specifically in presomitic mesoderm (Hayashi et al. 2018). Hes7 represses its own expression by binding two E-box sequences in its promoter, which causes oscillatory expression during somitogenesis (Hayashi et al. 2018). |
| (summation) | [BlackBoxEvent:9824253] Expression of Hes7 in presomitic mesoderm [Mus musculus] |
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No pathways have been reviewed or authored by The Notch1 intracellular domain (Nicd from Notch signaling) ... (9824274)
