Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Tbx6 binds two sites approximately 1.3 kb upstream of the tr...

Class:IdSummation:9824246
_displayNameTbx6 binds two sites approximately 1.3 kb upstream of the tr...
_timestamp2023-02-02 17:45:38
created[InstanceEdit:9824212] May, Bruce, 2023-01-18
modified[InstanceEdit:9825334] May, Bruce, 2023-01-25
[InstanceEdit:9827751] May, Bruce, 2023-02-02
textTbx6 binds two sites approximately 1.3 kb upstream of the transcription start site of Hes7 (González et al. 2013). Lef1:Ctnnb1 and the Notch intracellular domain (Nicd) complexed with Rbpj also bind within the upstream 2.6 kb of the Hes7 promoter and activate transcription (González et al. 2013).
(summation)[Reaction:9824206] Lef1:Ctnnb1, Nicd (Notch), and Tbx6 bind the Hes7 gene in presomitic mesoderm [Mus musculus]
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