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Query author contributions in Reactome

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Details on Person FXa inhibitors bind FXa mimetic

Class:IdReaction:9823296
_displayNameFXa inhibitors bind FXa mimetic
_doReleaseTRUE
_timestamp2026-01-27 16:14:44
authored[InstanceEdit:9929032] Shamovsky, Veronica, 2024-11-20
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:9823294] Shamovsky, Veronica, 2023-01-05
disease[Disease:9696604] blood coagulation disease
edited[InstanceEdit:9937613] Shamovsky, Veronica, 2025-02-05
input[DefinedSet:9038743] Factor Xa inhibitors [extracellular region]
[ProteinDrug:9823325] andexanet alfa [extracellular region]
internalReviewed[InstanceEdit:9936123] D'Eustachio, Peter, 2025-01-20
isChimericFALSE
literatureReference[LiteratureReference:9823299] A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa
[LiteratureReference:9823293] Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors
[LiteratureReference:9823457] Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban by Andexanet Alfa as Measured by Whole Blood Thromboelastographic Analysis
modified[InstanceEdit:9823473] Shamovsky, Veronica, 2023-01-06
[InstanceEdit:9823573] Shamovsky, Veronica, 2023-01-07
[InstanceEdit:9938575] Shamovsky, Veronica, 2025-02-18
[InstanceEdit:9938661] Shamovsky, Veronica, 2025-02-18
[InstanceEdit:9938855] Shamovsky, Veronica, 2025-02-20
[InstanceEdit:9979505] Shamovsky, Veronica, 2026-01-20
[InstanceEdit:9980341] Shamovsky, Veronica, 2026-01-27
nameFXa inhibitors bind FXa mimetic
output[Complex:9823300] andexanet alfa:factor Xa inhibitors [extracellular region]
releaseDate2026-03-25
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9823340] R-HSA-9823296.1
summation[Summation:9823306] This Reactome event shows binding of andexanet alfa to direc...
(hasEvent)[Pathway:9769739] Regulation of clotting cascade [Homo sapiens]
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No pathways have been reviewed or authored by FXa inhibitors bind FXa mimetic (9823296)