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Details on Person DIS3L2 hydrolyzes uridylated mRNA

Class:IdBlackBoxEvent:9822437
_displayNameDIS3L2 hydrolyzes uridylated mRNA
_doReleaseTRUE
_timestamp2023-08-08 17:54:46
authored[InstanceEdit:9822429] May, Bruce, 2022-12-23
catalystActivity[CatalystActivity:9822434] 3'-5'-RNA exonuclease activity of DIS3L2:PABPN1:uridylated partially deadenylated mRNA complex [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9822431] May, Bruce, 2022-12-23
edited[InstanceEdit:9822429] May, Bruce, 2022-12-23
inferredFrom
input[Complex:9820886] DIS3L2:PABPN1:uridylated partially deadenylated mRNA complex [cytosol] [Homo sapiens]
[SimpleEntity:29356] H2O [cytosol]
isChimericFALSE
modified[InstanceEdit:9827267] May, Bruce, 2023-01-31
[InstanceEdit:9841067] May, Bruce, 2023-08-08
nameDIS3L2 hydrolyzes uridylated mRNA
output[EntityWithAccessionedSequence:9820867] DIS3L2 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:9822424] PABPN1 [cytosol] [Homo sapiens]
precedingEvent
releaseDate2023-09-13
reviewed[InstanceEdit:9841065] Xie, Wei, 2023-08-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9822439] R-HSA-9822437.1
summation[Summation:9822436] PABPN1 bound to 3' uridylated mRNA recruits DIS3L2, an exoso...
(hasEvent)[Pathway:9820865] Z-decay: degradation of maternal mRNAs by zygotically expressed factors [Homo sapiens]
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No pathways have been reviewed or authored by DIS3L2 hydrolyzes uridylated mRNA (9822437)
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