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Details on Person CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA

Class:Id	Reaction:9822335
_displayName	CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA
_doRelease	TRUE
_timestamp	2023-08-08 17:54:06
authored	[InstanceEdit:9822274] May, Bruce, 2022-12-22
catalystActivity	[CatalystActivity:9822342] poly(A)-specific ribonuclease activity of CCR4-NOT(CNOT6L):ZFP36L2:mRNA [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9822305] May, Bruce, 2022-12-23
edited	[InstanceEdit:9822274] May, Bruce, 2022-12-22
inferredFrom	[Reaction:9822332] CCR4-NOT(Cnot6l) deadenylates mRNA in CCR4-NOT(Cnot6l):Zfp36l2:mRNA [Mus musculus]
input	[Complex:9819254] CCR4-NOT(CNOT6L):ZFP36L2:mRNA [cytosol] [Homo sapiens] [SimpleEntity:29356] H2O [cytosol]
isChimeric	FALSE
modified	[InstanceEdit:9822429] May, Bruce, 2022-12-23 [InstanceEdit:9827267] May, Bruce, 2023-01-31 [InstanceEdit:9841067] May, Bruce, 2023-08-08
name	CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA
output	[Complex:9822334] CCR4-NOT(CNOT6L):ZFP36L2:deadenylated mRNA [cytosol] [Homo sapiens] [SimpleEntity:76577] AMP [cytosol]
precedingEvent	[Reaction:9819200] ZFP36L2 binds CNOT6L of CCR4-CNOT complex and an AU-rich element in mRNA [Homo sapiens]
releaseDate	2023-09-13
reviewed	[InstanceEdit:9841065] Xie, Wei, 2023-08-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9822380] R-HSA-9822335.1
summation	[Summation:9822420] ZFP36L2 bound to AU-rich elements of specific mRNAs recruits...
(hasEvent)	[Pathway:9820841] M-decay: degradation of maternal mRNAs by maternally stored factors [Homo sapiens]
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No pathways have been reviewed or authored by CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA (9822335)